顱內(nèi)動(dòng)脈瘤介入治療的療效評(píng)價(jià)
發(fā)布時(shí)間:2018-03-10 16:12
本文選題:顱內(nèi)動(dòng)脈瘤 切入點(diǎn):介入治療 出處:《昆明醫(yī)科大學(xué)》2015年碩士論文 論文類型:學(xué)位論文
【摘要】:研究背景顱內(nèi)動(dòng)脈瘤是顱內(nèi)動(dòng)脈管壁的局限性異常膨出,在腦血管疾病病因中位居第3位,是造成蛛網(wǎng)膜下腔出血(subarachnoid hemorrhage,SAH)的首位病因,其死亡率和致殘率很高。隨著介入技術(shù)和介入材料的不斷發(fā)展,血管內(nèi)治療已成為顱內(nèi)動(dòng)脈瘤的首選治療方法。但是,介入治療作為一種微創(chuàng)技術(shù),其手術(shù)風(fēng)險(xiǎn)仍然無(wú)法避免,如術(shù)中動(dòng)脈瘤破裂、血栓事件及復(fù)發(fā)等。本研究對(duì)我科2年來(lái)收治的100例病例進(jìn)行回顧性分析,探討顱內(nèi)動(dòng)脈瘤介入治療的療效。研究目的分析介入治療顱內(nèi)動(dòng)脈瘤的手術(shù)并發(fā)癥發(fā)生率、臨床及影像學(xué)結(jié)果、動(dòng)脈瘤影像隨訪再通率,探討顱內(nèi)動(dòng)脈瘤介入治療的療效及如何更好地進(jìn)行顱內(nèi)動(dòng)脈瘤的介入治療。研究方法對(duì)我科2年來(lái)收治的100例病例進(jìn)行回顧性分析。將收集的數(shù)據(jù)制作成SPSS數(shù)據(jù),對(duì)臨床及影像學(xué)資料進(jìn)行歸納總結(jié),分析總體療效。根據(jù)動(dòng)脈瘤栓塞程度進(jìn)行分組,比較多組間影像學(xué)隨訪結(jié)果差異。所有統(tǒng)計(jì)資料用SPSS13.0統(tǒng)計(jì)分析系統(tǒng)進(jìn)行分析,當(dāng)P0.05時(shí)差異有統(tǒng)計(jì)學(xué)意義。研究結(jié)果100例患者,127枚動(dòng)脈瘤,栓塞術(shù)后即刻造影,102枚致密栓塞,14枚瘤頸殘瘤,11枚部分栓塞。術(shù)中動(dòng)脈瘤破裂11例,器械相關(guān)并發(fā)癥4例。研究結(jié)論血管內(nèi)治療作為顱內(nèi)動(dòng)脈瘤的首選治療方法是安全、有效的,但仍然有風(fēng)險(xiǎn),如術(shù)中動(dòng)脈瘤破裂,術(shù)中或術(shù)后血栓形成,術(shù)后再通等。要想提高介入治療的療效,盡量減少或避免術(shù)中及術(shù)后并發(fā)癥的發(fā)生,就要采取積極的預(yù)防措施,最大努力地做好圍手術(shù)期處理,另外,術(shù)中根據(jù)動(dòng)脈瘤的具體部位、形態(tài)、大小及其與載瘤動(dòng)脈的關(guān)系而采用適合的介入治療方法是至關(guān)重要的。
[Abstract]:Background Intracranial aneurysm is the local abnormal bulge of intracranial artery wall, which is the third cause of cerebrovascular disease and the first cause of subarachnoid hemorrhage (SAH). With the continuous development of interventional technology and interventional materials, endovascular treatment has become the first choice for the treatment of intracranial aneurysms. However, as a minimally invasive technique, the surgical risk of interventional therapy is still unavoidable. In this study, 100 cases of aneurysm rupture, thrombus and recurrence in our department were retrospectively analyzed. Objective to investigate the effect of interventional therapy on intracranial aneurysms. To explore the curative effect of interventional treatment of intracranial aneurysms and how to better carry out interventional treatment of intracranial aneurysms. Methods 100 cases of intracranial aneurysms treated in our department in the past 2 years were retrospectively analyzed. The collected data were made into SPSS data. The clinical and imaging data were summarized and the overall curative effect was analyzed. According to the degree of embolism of aneurysm, the difference of imaging follow-up results among different groups was compared. All statistical data were analyzed by SPSS13.0 statistical analysis system. Results there were 127 aneurysms in 100 patients and 11 partial embolization of 14 cervical residual tumors in 102 dense embolization cases immediately after embolization. 11 cases of aneurysms ruptured during the operation. Conclusion Endovascular therapy is safe and effective as the first choice for the treatment of intracranial aneurysms, but there are still risks, such as rupture of aneurysms during operation, thrombosis during or after operation. If we want to improve the curative effect of interventional therapy and minimize or avoid complications during and after operation, we should take active preventive measures and do our utmost to handle the perioperative period well. In addition, It is very important to adopt appropriate interventional therapy according to the location, shape, size of aneurysm and its relationship with the aneurysm carrier artery.
【學(xué)位授予單位】:昆明醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2015
【分類號(hào)】:R743
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