本文關(guān)鍵詞： 高血壓病 血管迷走性暈厥 直立傾斜試驗　出處：《揚州大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的： (1).觀察伴或不伴有高血壓病的血管迷走性暈厥患者的臨床特點及實驗室指標(biāo),探索血管迷走性暈厥潛在的病理生理學(xué)機制。分析兩組患者直立傾斜試驗中血壓變化、住院期間用藥方案及治療轉(zhuǎn)歸,探討合并高血壓病的血管迷走性暈厥患者合理的治療方案。 (2).比較所有入選血管迷走性暈厥患者服用β受體阻滯劑情況,分析β受體阻滯劑在血管迷走性暈厥中的作用。 方法： 統(tǒng)計分析出院診斷為血管迷走性暈厥合并高血壓病的30例住院患者與單純診斷血管迷走性暈厥30例住院患者的臨床特點,與納入的30例健康體檢者比較三組間的一般情況及實驗室指標(biāo),并通過記錄比較伴或不伴高血壓病的血管迷走性暈厥患者兩組間直立傾斜試驗中的血壓變化及治療特點,評價合并高血壓病的血管迷走性暈厥患者的臨床特點及合適的治療方案。 結(jié)果： (1).伴或不伴高血壓病的血管迷走性暈厥患者與健康對照組間一般資料、實驗室指標(biāo)差異無統(tǒng)計學(xué)意義(P0.05)。 (2).伴高血壓病的血管迷走性暈厥患者平臥位血壓顯著高于不伴高血壓的血管迷走性暈厥患者(P0.05),傾斜后兩組之間血壓變化無統(tǒng)計學(xué)意義(P0.05)。 (3).在降壓藥物應(yīng)用方面,合并高血壓病的血管迷走性暈厥患者有80%堅持服用降壓藥物控制血壓。 (4).合并高血壓病的VVS患者中共有11例(36.7%)服用β受體阻滯劑藥物進行治療,非高血壓病的VVS患者中有4例(13%)服用p受體阻滯劑藥物進行治療,兩組間指標(biāo)差異有統(tǒng)計學(xué)意義(P0.05)。服或不服用p受體阻滯劑藥物的血管迷走性暈厥患者在年齡、性別、入院時心率、病程、暈厥發(fā)作誘因及暈厥先兆、發(fā)作次數(shù)、持續(xù)時間等方面差異性均無統(tǒng)計學(xué)意義(P0.05)。 結(jié)論： (1).合并高血壓病的血管迷走性暈厥患者平臥位血壓明顯高于不伴高血壓的血管迷走性暈厥患者,傾斜后血壓兩組間變化無顯著性差異。對合并高血壓病的血管迷走性暈厥患者應(yīng)選擇合理的降壓和綜合治療方案。 (2).β受體阻滯劑是目前治療血管迷走性暈厥的基本藥物,有關(guān)β受體阻滯劑在血管迷走性暈厥治療中的價值和特異性尚需擴大樣本進一步研究。
[Abstract]:Objective:. To observe the clinical characteristics and laboratory indexes of vasovagal syncope with or without hypertension, and to explore the underlying pathophysiological mechanism of vasovagal syncope. To explore the rational treatment of vasovagal syncope complicated with hypertension. To compare the effects of 尾 receptor blockers on vasovagal syncope in all patients with vasovagal syncope. Methods:. The clinical features of 30 patients with vasovagal syncope complicated with hypertension and 30 patients with vasovagal syncope diagnosed by simple diagnosis of vasovagal syncope were analyzed statistically. The general situation and laboratory indexes of the three groups were compared with 30 healthy persons, and the changes of blood pressure and the characteristics of treatment in the vertical tilt test between the two groups were recorded and compared with or without hypertension. To evaluate the clinical features and appropriate treatment of vasovagal syncope complicated with hypertension. Results:. There was no significant difference in laboratory indexes between patients with vasovagal syncope with or without hypertension and healthy control group (P 0.05). The blood pressure in supine position in patients with vasovagal syncope with hypertension was significantly higher than that in patients with vasovagal syncope without hypertension (P 0.05). 80% patients with vasovagal syncope with hypertension take antihypertensive drugs to control blood pressure. A total of 11 VVS patients with hypertension were treated with beta-receptor blockers, and four patients with non-hypertensive VVS were treated with p-receptor blockers. The difference between the two groups was statistically significant (P 0.05). Patients with vasovagal syncope who took or did not take p receptor blockers were treated with age, sex, heart rate at admission, course of illness, onset of syncope, symptoms of syncope, frequency of attack. The difference of duration was not statistically significant (P 0.05). Conclusion:. In patients with vasovagal syncope complicated with hypertension, the blood pressure in supine position was significantly higher than that in patients with vasovagal syncope without hypertension. There was no significant difference in blood pressure between the two groups after tilt. The patients with vasovagal syncope complicated with hypertension should choose reasonable hypotension and comprehensive treatment. 尾 -blocker is a basic drug for the treatment of vasovagal syncope. The value and specificity of 尾 -blocker in the treatment of vasovagal syncope need to be further studied.
【學(xué)位授予單位】：揚州大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R741

【參考文獻】

相關(guān)期刊論文 前6條

1 況煒,陳瑩瑩,沈岳良,夏強;鐵抑制血管舒張活動及其作用機制[J];中國病理生理雜志;2003年11期

2 何作云,馮兵,文芳;高血壓病左心室肥厚紅細胞變形性的變化機制及其意義(摘要)[J];中國循環(huán)雜志;1998年01期

3 胡兆霆,胡駿,楊鈞國,陳志堅,李裕舒,龐紅;血管迷走性暈厥患者神經(jīng)體液激活及其對壓力反射敏感性的影響[J];中華心律失常學(xué)雜志;2001年03期

4 劉國仗,陳孟勤,周北凡,張維忠,惠汝太;我國高血壓病研究的主要成就[J];中華心血管病雜志;1999年04期

5 賈三慶,李莉,郭春艷;血管內(nèi)皮功能與迷走神經(jīng)性暈厥的關(guān)系[J];中華心血管病雜志;2004年04期

6 任自文,吳寧,陳孟揚,李儉春,胡大一,郭林妮,黃從新,黃德嘉,蔣文平;傾斜試驗用于診斷血管迷走性暈厥的建議[J];中華心血管病雜志;1998年05期

，

本文編號：1537233