本文關(guān)鍵詞： 腦卒中 發(fā)病 影響因素 高血壓患者 隊(duì)列研究 Cox回歸分析　出處：《中國(guó)公共衛(wèi)生》2016年06期 　論文類(lèi)型：期刊論文

【摘要】：目的了解高血壓患者腦卒中發(fā)病影響因素,為腦卒中的預(yù)防控制提供參考依據(jù)。方法采用前瞻性隊(duì)列研究方法于2010年1月,在江蘇省5個(gè)高血壓社區(qū)規(guī)范化管理基地隨機(jī)抽取12 893例高血壓患者進(jìn)行問(wèn)卷調(diào)查、體格檢查和實(shí)驗(yàn)室檢測(cè),并就高血壓患者的血壓控制情況、腦卒中發(fā)生情況和死亡情況于2011—2014年每年進(jìn)行1次隨訪,采用單因素和多因素Cox回歸分析方法分析高血壓患者腦卒中發(fā)病的影響因素。結(jié)果江蘇省隨訪的12 893例高血壓患者隨訪時(shí)間為0.7~58.1個(gè)月,平均隨訪時(shí)間為(43.4±10.2)個(gè)月,共失訪554例,失訪率為4.30%;隨訪結(jié)束時(shí)高血壓患者腦卒中發(fā)病331例,腦卒中發(fā)病率為2.68%;多因素Cox回歸分析結(jié)果顯示,年齡≥45歲、高血壓病程5年、有腦卒中家族史、收縮壓≥180 mm Hg和左心室肥厚為高血壓患者腦卒中發(fā)病的危險(xiǎn)因素,女性和文化程度初中及以上為高血壓患者腦卒中發(fā)病的保護(hù)因素。結(jié)論性別、年齡、文化程度、高血壓病程、腦卒中家族史、收縮壓和左心室肥厚是高血壓患者發(fā)生腦卒中的主要影響因素。
[Abstract]:Objective to investigate the influencing factors of stroke in patients with hypertension and to provide reference for the prevention and control of stroke. Methods A prospective cohort study was conducted on January 2010. A total of 12 893 hypertension patients were randomly selected from 5 hypertension community standardized management bases in Jiangsu Province for questionnaire investigation, physical examination and laboratory examination. The incidence and death of stroke were followed up once a year in 2011-2014, Univariate and multivariate Cox regression analysis was used to analyze the influencing factors of stroke in patients with hypertension. Results 12 893 patients with hypertension were followed up in Jiangsu Province for 0.7 ~ 58.1 months, with an average follow-up time of 43.4 鹵10.2 months. At the end of follow-up, 331 cases of hypertensive stroke and 2.68% of stroke incidence were found. The results of multivariate Cox regression analysis showed that age 鈮，

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