本文關(guān)鍵詞： 大腦中動(dòng)脈 狹窄 病理性 腦梗塞 經(jīng)顱多普勒 微栓子信號(hào)　出處：《現(xiàn)代實(shí)用醫(yī)學(xué)》2015年04期 　論文類(lèi)型：期刊論文

【摘要】：目的探討微栓子信號(hào)(MES)與大腦中動(dòng)脈狹窄(MCAS)的相關(guān)性。方法選取癥狀性MCAS患者70例,無(wú)癥狀性MCAS患者20例;癥狀性MCAS組又分為短暫性腦缺血發(fā)作(TIA)組14例和腦梗死組56例。所有患者均行頭顱MRI證實(shí)有無(wú)梗死灶,并記錄梗死部位;行CT血管成像(CTA)或數(shù)字減影血管造影(DSA)對(duì)大腦中動(dòng)脈有無(wú)狹窄以及狹窄程度進(jìn)行分級(jí);行MES監(jiān)測(cè),記錄栓子數(shù)量、部位。結(jié)果癥狀性MCAS組MES陽(yáng)性率高于無(wú)癥狀組(0.05);癥狀性MCAS組,輕、中、重度狹窄3組的MES陽(yáng)性率差異有統(tǒng)計(jì)學(xué)意義(0.05);癥狀性MCAS組MES陽(yáng)性的患者美國(guó)國(guó)立衛(wèi)生院神經(jīng)功能缺損評(píng)分(NIHSS)低于陰性患者(0.05);癥狀性MCAS組交界區(qū)梗死和散發(fā)皮質(zhì)小梗死MES陽(yáng)性率明顯高于其他梗死類(lèi)型(0.05)。結(jié)論充分評(píng)估腦血管影像學(xué)檢查,結(jié)合MES監(jiān)測(cè),對(duì)于不同類(lèi)型的腦梗死采用個(gè)體化治療。
[Abstract]:Objective to investigate the relationship between microembolus signal and middle cerebral artery stenosis (MCAS). Methods 70 patients with symptomatic MCAS and 20 patients with asymptomatic MCAS were selected. The symptomatic MCAS group was divided into two groups: TIA group (n = 14) and cerebral infarction group (n = 56). All the patients were confirmed by cranial MRI and the location of infarction was recorded. Ct angiography and digital subtraction angiography were used to grade middle cerebral artery stenosis and degree of stenosis. MES monitoring was performed to record the number and location of emboli. Results the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group, the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group, and in symptomatic MCAS group, the positive rate of MES in symptomatic MCAS group was higher than that in asymptomatic MCAS group. Light, medium, There were significant differences in MES positive rate among the three groups with severe stenosis, the MES positive MES score in the symptomatic MCAS group was lower than that in the negative MCAS group, and the infarct and sporadic cortex in the symptomatic MCAS group were smaller than those in the symptomatic MCAS group. The positive rate of MES in infarction was significantly higher than that in other types of infarction. Combined with MES monitoring, individual treatment was used for different types of cerebral infarction.
【作者單位】： 寧波大學(xué)醫(yī)學(xué)院附屬醫(yī)院;浙江大學(xué)醫(yī)學(xué)院附屬第二醫(yī)院;
【基金】：浙江省科技廳項(xiàng)目(2012C33117)
【分類(lèi)號(hào)】：R743.3

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