本文關(guān)鍵詞： 腦梗死 尿酸 預(yù)后 神經(jīng)功能缺損量表 改良Rankin量表　出處：《廣東醫(yī)學(xué)院學(xué)報(bào)》2016年06期 　論文類(lèi)型：期刊論文

【摘要】：目的觀察血尿酸水平對(duì)急性腦梗死患者神經(jīng)功能的影響。方法選擇急性腦梗死患者102例,根據(jù)其血尿酸水平分為高尿酸組(52例)和正常組(50例)。采用神經(jīng)功能缺損量表(NIHSS)和改良Rankin量表(MRS)評(píng)估兩組患者的神經(jīng)功能恢復(fù)情況,同時(shí)檢測(cè)入院后2周內(nèi)患者的血尿酸水平變化。結(jié)果高尿酸組治療2周NIHSS評(píng)分、治療6個(gè)月MRS評(píng)分和預(yù)后不良發(fā)生率均明顯低于正常組(P0.05),高尿酸組的好轉(zhuǎn)率明顯高于正常組(69.2%vs 50.0%,P0.05)。治療第2天,出現(xiàn)好轉(zhuǎn)和無(wú)好轉(zhuǎn)患者的血尿酸水平均明顯低于治療前(P0.05),且好轉(zhuǎn)患者的血尿酸水平低于無(wú)好轉(zhuǎn)者(P0.05)。結(jié)論血清高尿酸患者的神經(jīng)功能恢復(fù)和預(yù)后相對(duì)較好,可適當(dāng)補(bǔ)充尿酸以提高療效。
[Abstract]:Objective to observe the effect of serum uric acid level on nerve function in patients with acute cerebral infarction. Methods 102 patients with acute cerebral infarction were selected. According to the level of serum uric acid, 52 cases were divided into hyperuricemia group (n = 52) and normal group (n = 50). To evaluate the recovery of nerve function in both groups. At the same time, the changes of serum uric acid level were detected within 2 weeks after admission. Results the NIHSS score of hyperuricemia group was 2 weeks after treatment. The MRS score and the incidence of poor prognosis in the treatment group were significantly lower than those in the normal group (P 0.05), and the improvement rate in the high uric acid group was significantly higher than that in the normal group (69.2 vs 50.0%). On the second day of treatment, the levels of uric acid in patients with improvement and no improvement were significantly lower than those before treatment (P 0.05). The level of serum uric acid in the patients with improvement was lower than that in the patients without improvement (P 0.05). Conclusion the recovery of nerve function and prognosis of patients with serum hyperuricemia are relatively good, which can be improved by appropriate supplementation of uric acid.
【作者單位】： 廣東省湛江市第二人民醫(yī)院神經(jīng)內(nèi)科;
【分類(lèi)號(hào)】：R743.33
【正文快照】： 腦血管疾病是繼心血管疾病及癌癥之后世界上第三高死亡率疾病,其中急性腦梗死起病急,病因復(fù)雜,致死率高,是首位致殘因素,給社會(huì)和家庭帶來(lái)巨大負(fù)擔(dān)。近年來(lái)因人口老齡化等原因,我國(guó)[1-3]急性腦梗死患病率逐年增加,日益受到關(guān)注。尿酸是體內(nèi)嘌呤代謝的最終產(chǎn)物,比DNA更容易被單

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