本文關(guān)鍵詞：研究拉莫三嗪單藥治療小兒失神癲癇的臨床效果　出處：《中國實用醫(yī)藥》2016年31期 　論文類型：期刊論文

  更多相關(guān)文章： 拉莫三嗪 單藥治療 小兒失神癲癇 療效

【摘要】：目的 探討拉莫三嗪單藥治療小兒失神癲癇的臨床效果。方法 80例小兒失神癲癇病患兒作為研究對象,依據(jù)不同治療方法 分為觀察組與對照組,各40例。對照組采用丙戊酸鈉治療,觀察組采用拉莫三嗪單藥治療,對比兩組臨床療效。結(jié)果 治療后3個月,觀察組患兒治療總有效率為95.00%,明顯高于對照組的77.50%,差異有統(tǒng)計學(xué)意義(P0.05)。觀察組患兒在用藥治療期間出現(xiàn)3例不良反應(yīng)癥狀,其中1例惡心、1例皮疹、1例記憶力衰退,不良反應(yīng)發(fā)生率為7.50%;對照組患兒在用藥治療期間出現(xiàn)8例不良反應(yīng)癥狀,其中2例惡心、2例皮疹、1例記憶力衰退、3例頭痛,不良反應(yīng)發(fā)生率20.00%;觀察組不良反應(yīng)發(fā)生率顯著低于對照組,差異有統(tǒng)計學(xué)意義(P0.05)。結(jié)論 拉莫三嗦單藥治療小兒失神癲癇效果確切,短期內(nèi)總有效率高,安全可靠,值得推廣應(yīng)用。
[Abstract]:Objective to explore the clinical effect of lamotrigine monotherapy in the treatment of childhood absence epilepsy. Methods 80 cases of childhood absence epilepsy patients as the research object, according to the different treatment methods were divided into observation group and control group, 40 cases in each group. The observation group was treated with sodium valproate, lamotrigine monotherapy, compared the clinical efficacy of two groups. Results after treatment 3 months, the total efficiency of the observation group was 95%, significantly higher than the control group 77.50%, the difference was statistically significant (P0.05). The symptoms of adverse reactions occurred in 3 cases of observation group during the treatment, including 1 cases of nausea, 1 cases of skin rash, 1 cases of memory loss, the incidence rate of adverse reaction was 7.50%; the symptoms of adverse reactions occurred in 8 patients in control group during the treatment, including 2 cases of nausea, 2 cases of skin rash, 1 cases of memory loss, headache in 3 cases, the incidence of adverse reactions was 20%; the observation group adverse reaction rate. The lower than the control group, the difference was statistically significant (P0.05). Conclusion three Suo monotherapy Rameau in childhood absence epilepsy is effective in the short term, the total effective rate is high, safe and reliable, it is worthy of popularization and application.

【作者單位】： 內(nèi)蒙古自治區(qū)人民醫(yī)院兒科;
【正文快照】： 小兒失神癲癇作為典型的神經(jīng)系統(tǒng)異常特發(fā)性全身癲癇病癥,其4~9歲階段為該病癥高發(fā)期。目前臨床中治療該病主要采用丙戊酸鈉藥物抗癲癇,其療效對于原發(fā)性或初次失神癥狀者尚有一定療效,不過復(fù)雜性失神療效不足,并且有著一定的藥物不良反應(yīng)[1],為患者帶來不小的痛苦。拉莫三嗪，

本文編號：1423277