急性腦梗死患者同型半胱氨酸與頸動脈斑塊的相關(guān)分析
發(fā)布時間:2017-12-27 23:25
本文關(guān)鍵詞:急性腦梗死患者同型半胱氨酸與頸動脈斑塊的相關(guān)分析 出處:《臨床醫(yī)藥文獻電子雜志》2016年48期 論文類型:期刊論文
更多相關(guān)文章: 頸動脈斑塊 腦梗死 多普勒超聲 同型半胱氨酸
【摘要】:目的分析急性腦梗死患者同型半胱氨酸與頸動脈斑塊的相關(guān)性。方法選取2015年6月~2016年6月我院急性腦梗死患者100例為研究對象,將有斑塊的患者分為研究組,無斑塊患者分為常規(guī)組,各50例。使用彩色多普勒超聲檢測患者頸動脈粥樣硬化斑塊的有無,以及斑塊厚度、膜厚度。發(fā)病3d內(nèi)測量血清HCY水平。結(jié)果研究組HCY中位數(shù)為12.5μmol/L,常規(guī)組HCY中位數(shù)為15.6μmol/L,Spearman檢驗表明頸動脈斑塊最大厚度與HCY關(guān)系為正相關(guān),差異有統(tǒng)計學(xué)意義(r=0.235,P0.05);仡櫺苑治鯨ogistic表明,患者年齡、高血壓病史、男性性別是影響斑塊形成的主要原因,而HCY與斑塊形成無關(guān)系,HCY與頸動脈斑塊最大厚度關(guān)系為正相關(guān)。結(jié)論研究組患者HCY明顯高于常規(guī)組,HCY與頸脈動斑塊最大厚度關(guān)系,呈正相關(guān)。
[Abstract]:Objective to analyze the correlation between homocysteine (homocysteine) and carotid plaque in patients with acute cerebral infarction. Methods a total of 100 patients with acute cerebral infarction in our hospital from June 2015 to June ~2016 were selected as the research subjects. Patients with plaques were divided into study group, and no plaques were divided into routine group and 50 case group. Color Doppler ultrasound was used to detect the carotid atherosclerotic plaque, and the thickness of plaque and the thickness of the membrane. Serum levels of HCY were measured in 3D. Results the median of HCY in the study group was 12.5 mol/L, and the median HCY in the conventional group was 15.6 mol/L. The Spearman test showed that the relationship between the maximum thickness of carotid plaques and HCY was positively correlated, and the difference was statistically significant (r=0.235, P0.05). A retrospective analysis of Logistic showed that age, history of hypertension and male sex were the main causes of plaque formation. HCY was not correlated with plaque formation. HCY was positively correlated with the maximum thickness of carotid plaques. Conclusion the HCY of the patients in the study group was significantly higher than that of the conventional group, and the relationship between HCY and the maximum thickness of the cervical pulsating plaque was positively correlated.
【作者單位】: 南京鼓樓醫(yī)院集團宿遷市人民醫(yī)院;
【分類號】:R743.33
【正文快照】: 頸動脈斑塊是影響缺血性卒中最主要的一個危險原因,有關(guān)研究表明,頸動脈斑塊患者的同型半胱氨酸明顯高于其他人群[1]。但是針對急性腦梗死患者而言,HCY與頸脈動斑塊最大厚度之間的關(guān)系,尚未完全明確[2]。本文就此探討急性腦梗死患者同型半胱氨酸與頸動脈斑塊的相關(guān)性,F(xiàn)報道
【參考文獻】
相關(guān)博士學(xué)位論文 前1條
1 魯U,
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