本文關(guān)鍵詞：血脂水平與動脈瘤性蛛網(wǎng)膜下腔出血后遲發(fā)性腦缺血的相關(guān)性　出處：《中國臨床神經(jīng)外科雜志》2016年11期 　論文類型：期刊論文

  更多相關(guān)文章： 動脈瘤性蛛網(wǎng)膜下腔出血 遲發(fā)性腦缺血 血脂 改良Fisher分級

【摘要】：目的探討血脂水平與動脈瘤性蛛網(wǎng)膜下腔出血(a SAH)后遲發(fā)性腦缺血(DCI)的相關(guān)性。方法回顧性分析2014年1月至2015年12月收治的74例a SAH的臨床資料,采用多因素Logistic回歸分析檢驗性別、年齡、動脈瘤位置、動脈瘤大小、世界神經(jīng)外科醫(yī)師聯(lián)盟(WFNS)分級、改良Fisher分級、Hunt-Hess分級、治療方式、總甘油三脂、總膽固醇、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇、脂蛋白(a)、載脂蛋白A、載脂蛋白B等因素與DCI的關(guān)系。結(jié)果 74例中,65例入院后檢測血脂,20例出現(xiàn)DCI,45例未出現(xiàn)DCI,a SAH后DCI的發(fā)生率為30.8%。多因素Logistic回歸分析顯示高甘油三酯及改良Fisher分級是a SAH后DCI發(fā)生的獨立危險因素。結(jié)論及時檢測a SAH患者的血脂水平和對患者進(jìn)行改良Fisher分級對DCI的診斷治療均有參考價值。
[Abstract]:Objective to investigate the correlation between blood lipid level and delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (a SAH). Methods Retrospective analysis of clinical data from January 2014 to December 2015 were 74 cases of a SAH, multivariate Logistic regression analysis was used to test gender and age, aneurysm location, aneurysm size, the world alliance of neurosurgeons (WFNS) grade, modified Fisher grade, Hunt-Hess grade, treatment, total glycerin three fat, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, lipoprotein (a), the relationship between DCI factor and apolipoprotein A, apolipoprotein B etc.. Results of the 74 cases, 65 cases were tested for blood lipid, 20 cases had DCI, 45 cases had no DCI, and the incidence of DCI after a SAH was 30.8%. Multifactor Logistic regression analysis showed that high triglyceride and improved Fisher classification were independent risk factors for DCI after a SAH. Conclusion the timely detection of blood lipid levels in a SAH patients and the improved Fisher classification for patients are of reference value for the diagnosis and treatment of DCI.
【作者單位】： 石河子大學(xué)醫(yī)學(xué)院第一附屬醫(yī)院神經(jīng)外科;
【基金】：國家科技支撐計劃(2013BAI05B05)
【分類號】：R743.35
【正文快照】： 蛛網(wǎng)膜下腔出血(subrachnoid hemorrhage,SAH)指腦底部或腦表面的病變血管破裂,血液直接流入蛛網(wǎng)膜下腔引起的一種臨床綜合征,是臨床常見的腦血管疾病,主要原因是顱內(nèi)動脈瘤破裂出血。動脈瘤性SAH(aneurysamal SAH,a SAH)致殘率、病死率均較高,與遲發(fā)性腦缺血(delayed cerebra，

本文編號：1338516