預(yù)防性給予止吐藥物的婦科患者發(fā)生術(shù)后惡心嘔吐的危險因素
發(fā)布時間:2018-03-17 22:39
本文選題:術(shù)后惡心嘔吐 切入點:婦科手術(shù) 出處:《中國醫(yī)科大學(xué)學(xué)報》2017年11期 論文類型:期刊論文
【摘要】:目的研究預(yù)防性給予止吐藥物的婦科患者發(fā)生術(shù)后惡心嘔吐(PONV)的危險因素。方法選擇行婦科手術(shù)的患者1 000例,收集患者基本資料以及麻醉、手術(shù)和其他資料,并于術(shù)后第1天進行惡心嘔吐的調(diào)查隨訪,對數(shù)據(jù)進行統(tǒng)計學(xué)分析。結(jié)果多因素logistic回歸分析納入暈動病史、鎮(zhèn)痛泵、麻醉時長、術(shù)畢應(yīng)用新斯的明,按OR值從大到小排序為暈動病史(OR=1.953,95%CI:1.404~2.716)、術(shù)畢應(yīng)用新斯的明(OR=1.831,95%CI:1.203~2.786)、鎮(zhèn)痛泵(OR=1.472,95%CI:1.017~2.129)、麻醉時長(OR=1.256,95%CI:1.058~1.492),預(yù)測模型為p=1(1+e~(1.623-0.669x-1-0.386x_2-0.228x_3-0.605x_4))。此模型判斷婦科患者PONV的準(zhǔn)確度為70.6%,預(yù)測結(jié)果ROC曲線下面積為0.642。結(jié)論預(yù)防性給予止吐藥物的婦科患者發(fā)生PONV的獨立危險因素按影響程度由大到小為暈動病史、術(shù)畢應(yīng)用新斯的明、鎮(zhèn)痛泵、麻醉時長。
[Abstract]:Objective to study the risk factors of postoperative nausea and vomiting (PONVV) in gynecological patients who were given antiemetic drugs. Methods 1 000 patients undergoing gynecological surgery were selected and their basic data, anesthesia, surgery and other data were collected. Results the multivariate logistic regression analysis included the history of motion sickness, analgesic pump, duration of anesthesia, and the application of neostigmine at the end of operation. According to OR value, the order of OR was 1.95395 CI: 1.4041.4042.716, after operation, the neostigous organ OR1.831t95CI1.203n 2.786C, the analgesic pump OR1.47295CI1.0172.129, the anaesthesia duration 1.25695CI1.0581.0581.492.The prediction model was p111e1 E 1.669x-1-0.386x2-0.228x3-0.605x40.The PONV of gynecological patients diagnosed by this model was 70.6, and the area of ROC curve predicted was 0.2644.The accuracy of prediction model was 0.669x-1-0.386x2-0.228x3-0.605x4. The independent risk factors for the occurrence of PONV in gynecological patients who were given prophylaxis of antiemetic drugs were history of motion according to the degree of influence from large to small. After operation, use neostigmine, analgesic pump, anaesthesia time.
【作者單位】: 中國醫(yī)科大學(xué)附屬盛京醫(yī)院麻醉科;
【分類號】:R614
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