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反復(fù)應(yīng)用碘消毒劑可否導(dǎo)致人體過(guò)量攝碘的研究

發(fā)布時(shí)間:2019-06-19 12:39
【摘要】: 背景:以碘元素為有效成分的消毒劑在醫(yī)學(xué)領(lǐng)域有著廣泛的應(yīng)用。外科醫(yī)生在術(shù)前進(jìn)行手部消毒時(shí),含碘消毒劑一直是在世界范圍內(nèi)最經(jīng)典的、應(yīng)用最廣的選擇。碘元素同時(shí)是甲狀腺激素的合成原料,碘的缺乏可引起多種甲狀腺疾病。2001年以來(lái),人們開(kāi)始認(rèn)識(shí)到,碘的攝入過(guò)量同樣可使多種甲狀腺疾病的發(fā)病率增加目的:探討外科醫(yī)生反復(fù)應(yīng)用含碘消毒劑進(jìn)行術(shù)前手部消毒是否會(huì)引起碘元素過(guò)量攝入。方法:使用國(guó)際公認(rèn)的測(cè)定方法對(duì)上海中山醫(yī)院長(zhǎng)期使用安爾碘刷手的外科醫(yī)生和器械護(hù)士的碘攝入水平進(jìn)行測(cè)定,并在該醫(yī)院使用新型消毒劑替換安爾碘之后對(duì)同樣的樣本再次進(jìn)行了測(cè)定,作為自身對(duì)照。結(jié)果:經(jīng)過(guò)對(duì)71例樣本和61例對(duì)照樣本的結(jié)果分析,發(fā)現(xiàn)該人群并不存在碘攝入過(guò)量,并且停用含碘消毒劑后該人群碘的攝入水平亦無(wú)顯著下降。
[Abstract]:Background: disinfectants with iodine as the effective ingredient are widely used in the field of medicine. Iodine disinfectant has always been the most classical and widely used choice in the world when surgeons disinfect their hands before operation. Iodine is also a synthetic raw material for thyroid hormones, and iodine deficiency can cause a variety of thyroid diseases. Since 2001, it has been recognized that excessive iodine intake can also increase the incidence of various thyroid diseases. Objective: to explore whether repeated application of iodine disinfectant to hand disinfection before operation by surgeons will cause excessive intake of iodine. Methods: the iodine intake levels of surgeons and instrument nurses who had been using Aneri brush hand for a long time in Zhongshan Hospital of Shanghai were measured by internationally recognized method, and the same samples were measured again after the hospital replaced with a new disinfectant as self-control. Results: through the analysis of 71 samples and 61 control samples, it was found that there was no excess iodine intake in this population, and there was no significant decrease in iodine intake level after discontinuing the use of iodine disinfectant.
【學(xué)位授予單位】:復(fù)旦大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2010
【分類號(hào)】:R187;R581

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