本文選題：2型糖尿病 + 流行�。� 參考：《南昌大學》2009年碩士論文

【摘要】： 目的:探索當前城市社區(qū)居民糖尿病(Diabetes Mellitus,DM)的流行特點及其影響因素,并觀察飲食和行為干預(yù)對2-DM患者血生化指標的影響,為進一步研究DM流行規(guī)律和綜合防控提供科學參考。 方法:采用整群隨機抽樣,對青山湖社區(qū)常住居民1310人的DM流行現(xiàn)況進行了調(diào)查(包括問卷、體檢、空腹血糖及血脂等生化指標檢查),并在上述基礎(chǔ)上對確診的66例2-DM患者的影響因素實施了鑲嵌病例研究,且采用前瞻性隨訪觀察66例2-DM患者為期一個月的飲食和行為干預(yù)的效果,即對干預(yù)前后的某些生化指標進行比較。 結(jié)果:(1)青山湖社區(qū)人群2-DM總患病率為5.04%,高于全國平均水平,其中男性為6.42%,女性為4.31%。隨著年齡的增長,DM的患病率逐漸增高.(2)在所有被查對象中超重及肥胖率(BMI≥24)為42.90%,且兩性人群隨著BMI增加,其DM患病率上升。超重者其SBP、DBP、Tc、TG、LDL、FBG均較BMI正常者高,而HDL較正常者低。(3)病例對照研究的單因素與多因素非條件Logistic回歸分析,顯示BMI與2-DM有關(guān)聯(lián),其OR值為2.548,兩者關(guān)系密切。文化程度偏低者DM患病率明顯高于文化程度高者,病因?qū)W分析提示,受教育程度越低,發(fā)生DM的危險性越高,其OR值為1.785。家族史研究表明,有DM家族史者其患該病的危險是無家族史的1.88倍,與目前大多數(shù)研究結(jié)果相近,有學者的病例對照研究報告提示,家族史作為2型DM的獨立危險因素(OR=2.612)。TG也是2型DM的危險因素(OR=2.785)。(4)IFG率為7.63%,隨著年齡增加,IFG受損率呈逐漸升高的趨勢,肥胖者IFG受損率明顯高于正常人群。(5)經(jīng)為期一個月的飲食和行為干預(yù)的隨訪觀察,對2-DM患者自我感受和某些生化指標的改善有一定效果,如FBG明顯下降。 結(jié)論:(1)該人群2-DM患病率為5.04%,高于全國平均水平,男性患病率高于女性,隨著年齡加大患病率上升,已婚者患病率偏低,文化程度偏低的患病率偏高,在職業(yè)上表現(xiàn)為公務(wù)員(腦力勞動者)高,個人經(jīng)濟收入低的人群中患病率較高;肥胖、高血壓人群中DM患病率明顯高于其他人群。(2)與DM患病相關(guān)的主要危險因素有TG偏高、BMI異常、文化程度偏低和DM家族史。(3)對66例2-DM患者實施為期一個月的飲食和行為控制,結(jié)果表明其在臨床表現(xiàn)和自我感覺方面有不同程度的改善,且FBG、Cr與干預(yù)前比較有明顯下降。
[Abstract]:Objective: to explore the epidemic characteristics and influencing factors of diabetes mellitus (DM) in urban community residents, and to observe the effect of diet and behavior intervention on the blood biochemical indexes of 2-DM patients, so as to provide scientific reference for further study on the prevalence of DM and comprehensive prevention and control. Methods: the prevalence of DM in 1310 residents of Qingshan Lake community was investigated by cluster random sampling (including questionnaire, physical examination). Fasting blood glucose, blood lipid and other biochemical indexes were examined. On the basis of the above, inlaid case study was carried out on the influencing factors of 66 patients with 2-DM. The effects of dietary and behavioral intervention for one month in 66 patients with 2-DM were observed prospectively, that is to say, some biochemical indexes before and after intervention were compared. Results the total prevalence of 2-DM in Qingshanhu community was 5.04, which was higher than the national average, among which 6.42 were male and 4.31 in female. The prevalence rate of overweight and obesity in all subjects was 42.90. The prevalence of DM in both sexes increased with the increase of BMI. The results of univariate and multivariate Logistic regression analysis showed that there was a correlation between BMI and 2-DM (OR = 2.548, OR = 2.548). The prevalence of DM was significantly higher in those with lower education level than in those with high education. Etiological analysis indicated that the lower the level of education, the higher the risk of DM, and the OR value was 1.785. Family history studies have shown that people with DM family history are 1.88 times more likely to develop the disease than those with no family history, which is close to the results of most current studies. Family history, as an independent risk factor for type 2 DM, was also a risk factor of type 2 DM, and the IFG rate was 7.63. The damage rate of IFG increased gradually with age. The rate of IFG damage in obese patients was significantly higher than that in normal subjects. (5) after one month's follow-up observation of diet and behavior intervention, there was a certain effect on the improvement of self-feeling and some biochemical indexes in patients with 2-DM, such as the decrease of FBG. Conclusion the prevalence rate of 2-DM in this population is 5.04, which is higher than the national average. The prevalence rate of male is higher than that of female. With the increase of age, the prevalence rate of married people is lower, and the prevalence rate of education is lower than that of female. In the professional performance of civil servants (mental workers) high, low personal income of the population with a higher prevalence; obesity, The main risk factors related to the prevalence of DM in hypertension population were higher than those in other groups. The main risk factors associated with DM were abnormal TG, low education and family history of DM. 66 patients with 2-DM were treated with diet and behavior control for one month. The results showed that its clinical manifestation and self-feeling were improved to some extent, and FBGG Cr decreased significantly compared with that before intervention.
【學位授予單位】：南昌大學
【學位級別】：碩士
【學位授予年份】：2009
【分類號】：R587.1;R181.3

【引證文獻】

相關(guān)期刊論文 前1條

1 劉艷;黃潤平;韓萍;張文靜;殷鋒科;王少光;;鄭州市某社區(qū)居民糖尿病危險因素分析[J];醫(yī)藥論壇雜志;2012年02期

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本文編號：1779452