本文選題：細菌性痢疾　切入點：發(fā)病率　出處：《現(xiàn)代預防醫(yī)學》2014年16期 　論文類型：期刊論文

【摘要】：目的了解江蘇省菌痢發(fā)病規(guī)律,分析菌型分布和藥物敏感性特征,為菌痢防治提供科學依據(jù)。方法采用描述流行病學方法對2010-2012年江蘇省菌痢監(jiān)測資料進行分析,同時應用血清凝集和K-B紙片法進行血清分型和藥物敏感性分析。結(jié)果2010-2012年江蘇省菌痢年均發(fā)病率為8.49/10萬,發(fā)病高峰是5-10月份,占3年總發(fā)病數(shù)的72.39%;在地區(qū)上呈散發(fā)態(tài)勢,常州、鎮(zhèn)江和徐州3市年均發(fā)病率最高;年齡分布以低年齡組為主,05歲組年均發(fā)病率最高。福氏志賀菌是優(yōu)勢菌群,其中F2a最多,占41.50%;宋內(nèi)志賀菌變化顯著。志賀菌對萘啶酸耐藥率最高,其次為氨芐西林、四環(huán)素和復方新諾明。所有檢測的抗生素中氨芐西林的耐藥率增長最快。結(jié)論2010-2012年江蘇省菌痢發(fā)病率較往年有所降低,志賀菌菌群比例變化顯著,耐藥及多重耐藥現(xiàn)象日益嚴重。
[Abstract]:Objective to understand the incidence law of bacillary dysentery in Jiangsu Province, analyze the distribution of bacterial type and the characteristics of drug sensitivity, and provide scientific basis for the prevention and treatment of bacillary dysentery. Methods the monitoring data of bacterial dysentery in Jiangsu Province from 2010 to 2012 were analyzed by descriptive epidemiological method. Results the average annual incidence of bacillary dysentery in Jiangsu Province from 2010 to 2012 was 8.49 / 100 thousand, with a peak incidence of May to October, accounting for 72.39 percent of the total incidence in three years. The average annual morbidity of Zhenjiang and Xuzhou was the highest, and the age distribution was the highest in the age group of 05 years old. Shigella flexneri was the dominant group, and F2a was the most. Shigella sonnei had the highest resistance to nalididinic acid, followed by ampicillin. The resistance rate of ampicillin to ampicillin was the fastest in all the antibiotics tested. Conclusion the incidence of bacillary dysentery in Jiangsu Province from 2010 to 2012 was lower than that in previous years, and the proportion of Shigella bacteria changed significantly. Drug resistance and multi-drug resistance are becoming more and more serious.
【作者單位】： 江蘇省疾病預防控制中心;
【基金】：江蘇省“十二五”科教興衛(wèi)工程(ZX201109)
【分類號】：R516.4;R181.3

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