本文關(guān)鍵詞： 過氧乙酸 穩(wěn)定性 殺菌效果 毒性　出處：《中國消毒學(xué)雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的觀察某過氧乙酸消毒性能,為實(shí)際使用提供科學(xué)依據(jù)。方法采用含量測(cè)試、定量殺菌試驗(yàn)、空氣消毒模擬試驗(yàn)、現(xiàn)場(chǎng)試驗(yàn)和毒性試驗(yàn),對(duì)該消毒液的穩(wěn)定性、消毒效果、毒性進(jìn)行判定。結(jié)果該消毒液過氧乙酸質(zhì)量分?jǐn)?shù)為16.03%,置37℃溫箱儲(chǔ)存90 d,有效成分含量下降2.18%。含100 mg/L過氧乙酸稀釋液作用5 min,對(duì)金黃色葡萄球菌和大腸桿菌殺滅對(duì)數(shù)值均大于5.00,該濃度下作用10 min,對(duì)木質(zhì)桌面和織物上自然菌消除對(duì)數(shù)值均大于1.00;1 000 mg/L過氧乙酸作用30 min,對(duì)枯草桿菌黑色變種芽孢懸液的殺滅對(duì)數(shù)值均大于5.00,該濃度按10 ml/m~3用量噴霧消毒后30 min,對(duì)空氣中的白色葡萄球菌殺滅率大于99.90%、對(duì)空氣中自然菌的消亡率大于90.0%。該過氧乙酸屬于低毒類,其最高應(yīng)用濃度5倍溶液(2.5%)屬實(shí)際無毒類;小鼠急性吸入LC502 h大于10 000 mg/(kg·bw);小鼠骨髓嗜多染紅細(xì)胞微核試驗(yàn)為陰性。結(jié)論該過氧乙酸性能穩(wěn)定,對(duì)細(xì)菌、真菌和細(xì)菌芽孢有良好的殺滅效果。常用濃度屬實(shí)際無毒,無致突變作用。
[Abstract]:Objective To observe the peracetic acid disinfection performance, provide a scientific basis for practical use. The content of test methods, quantitative germicidal test, air disinfection test, field test and toxicity test, the disinfection effect of the disinfection solution stability, toxicity were assessed. Results the disinfectant of peracetic acid concentration was 16.03%, the temperature of 37 DEG C box 90 d of storage, the content of effective components by 2.18%. containing 100 mg/L peracetic acid diluted 5 min of Staphylococcus aureus and Escherichia coli in killing values are greater than 5, the concentration of 10 min on the desktop and wooden fabric on the natural bacteria elimination of values are greater than 1; 1000 mg/L peracetic acid 30 min of Bacillus subtilis var.niger suspension killing logvalue was greater than 5, the concentration at 10 ml/m~3 dosage of 30 min after spray disinfection, the air of Staphylococcus aureus killing rate of more than 99.90% The demise of the natural bacteria in the air, the rate is more than 90.0%. the peracetic acid is low toxicity, the highest concentration of 5 times the application solution (2.5%) is actually non-toxic; acute inhalation of LC502 h is greater than 10000 mg/ (kg - BW); mouse micronucleus test was negative. Conclusion the performance of peracetic acid stability of bacteria, fungi and bacterial spores have good bactericidal effect. The concentration is practically non-toxic, non mutagenic.

【作者單位】： 湖南省疾病預(yù)防控制中心;
【分類號(hào)】：R187

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本文編號(hào)：1509561