【摘要】：初探微計算機斷層掃描技術(Micro-CT)分析種植體周圍骨小梁情況,介紹運用特定的感興趣區(qū)域(ROI)選擇辦法,對比分析不同時期種植體-骨界面骨結合情況。實驗動物為8只雄性Beagle犬,將每只犬雙側下頜第3、4前磨牙微創(chuàng)拔除,牙齦翻瓣后選擇相應拔牙窩的合適位置即刻植入種植體(規(guī)格為長度10.0 mm,直徑3.8 mm)各1顆。術后4周,隨機處死4只實驗犬,其余4只于種植術后8周時處死,術后4周及8周共有32枚種植體樣本,運用Micro CT掃描,使用特定ROI選擇方法進行分析研究對比。結果顯示術后4周與8周種植體周圍骨密度及骨小梁數(shù)目、厚度、形態(tài)等方面差異均有統(tǒng)計學意義(P0.05)。本實驗運用的選擇ROI方法客觀、合理、有效,最終ROI分析結果符合傳統(tǒng)骨愈合及種植體-骨結合理論,為臨床種植學研究提供了指導。
[Abstract]:The microcomputerized tomography (Micro-CT) was used to analyze the periosseous bone trabeculae of the implants. the (ROI) selection method of the specific region of interest was introduced to compare and analyze the bone bonding between the implant and the bone interface in different periods. In 8 male Beagle dogs, the 3rd and 4th premolars were removed by minimally invasive extraction of the 3rd and 4th premolars in each dog. After the gum flap was turned over, the suitable position of the corresponding tooth extraction fossa was selected for immediate implantation (1 mm in length and 1 mm in diameter). At 4 weeks after operation, 4 experimental dogs were randomly killed, and the other 4 dogs were killed at 8 weeks after implantation. 32 implantation samples were collected at 4 weeks and 8 weeks after operation. Micro CT scanning was used to analyze and compare them with specific ROI selection methods. The results showed that there were significant differences in bone mineral density, number, thickness and morphology between 4 weeks and 8 weeks after operation (P 0.05). The selected ROI method used in this experiment is objective, reasonable and effective. The final ROI analysis results are in accordance with the traditional theory of bone healing and implantation-bone union, which provides guidance for clinical implantation research.
【作者單位】： 安徽醫(yī)科大學第四附屬醫(yī)院口腔科;南京中醫(yī)藥大學附屬八一醫(yī)院口腔科;
【基金】：2013年度南京軍區(qū)醫(yī)學科技創(chuàng)新課題(編號:MS054)
【分類號】：R783.6

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