整合素α2β1與藥物性牙齦增生相關(guān)性的研究進(jìn)展
發(fā)布時(shí)間:2018-10-31 07:41
【摘要】:藥物性牙齦增生(DIGO)是指長(zhǎng)期服用某些藥物而引起的牙齦組織的纖維性增生和體積增大。牙齦細(xì)胞增多與胞外基質(zhì)尤其是膠原蛋白的大量沉積是其主要病理表現(xiàn)。近年來研究表明,整合素α2β1與膠原吞噬作用密切相關(guān),在DIGO的發(fā)生發(fā)展中發(fā)揮了重要作用。本文就整合素α2β1與DIGO相關(guān)性的研究進(jìn)展進(jìn)行綜述。
[Abstract]:Drug-induced gingival hyperplasia (DIGO) is a kind of fibrous hyperplasia and enlargement of gingival tissue caused by taking some drugs for a long time. The increase of gingival cells and the deposition of extracellular matrix, especially collagen, are the main pathological features of gingival cells. Recent studies have shown that integrin 偽 2 尾 1 is closely related to the phagocytosis of collagen and plays an important role in the genesis and development of DIGO. This paper reviews the research progress of the correlation between integrin 偽 2 尾 1 and DIGO.
【作者單位】: 口腔疾病研究國(guó)家重點(diǎn)實(shí)驗(yàn)室華西口腔醫(yī)院牙周病科(四川大學(xué));
【分類號(hào)】:R781.4
本文編號(hào):2301412
[Abstract]:Drug-induced gingival hyperplasia (DIGO) is a kind of fibrous hyperplasia and enlargement of gingival tissue caused by taking some drugs for a long time. The increase of gingival cells and the deposition of extracellular matrix, especially collagen, are the main pathological features of gingival cells. Recent studies have shown that integrin 偽 2 尾 1 is closely related to the phagocytosis of collagen and plays an important role in the genesis and development of DIGO. This paper reviews the research progress of the correlation between integrin 偽 2 尾 1 and DIGO.
【作者單位】: 口腔疾病研究國(guó)家重點(diǎn)實(shí)驗(yàn)室華西口腔醫(yī)院牙周病科(四川大學(xué));
【分類號(hào)】:R781.4
【相似文獻(xiàn)】
相關(guān)碩士學(xué)位論文 前3條
1 楊哲;鈣通道阻滯劑介導(dǎo)的藥物性牙齦增生的相關(guān)研究[D];山西醫(yī)科大學(xué);2015年
2 龔逸明;環(huán)孢素所致藥物性牙齦增生與牙周致病菌的相關(guān)性研究[D];復(fù)旦大學(xué);2008年
3 狄昌萍;間充質(zhì)—上皮作用在藥物性牙齦增生發(fā)生機(jī)制中的初探[D];南京醫(yī)科大學(xué);2011年
,本文編號(hào):2301412
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