【摘要】：目的觀察再礦化制劑酪蛋白磷酸肽-無定形磷酸鈣復合物(CPP-ACP)、含氟酪蛋白磷酸肽-無定形磷酸鈣復合物(CPP-ACPF)、含氟磷酸三鈣(TCP+F)和Duraphat保護漆對酸蝕乳牙釉質表面硬度和表面形態(tài)的影響。方法選取因滯留拔除的下頜乳中切牙制備離體牙釉質塊(硬度值280~330 HV)試件50個,并隨機分為對照組、CPP-ACP組、CPP-ACPF組、TCP+F組和Duraphat組。酸蝕處理所有試件(可口可樂,5次/d,5 min/次,共5 d),酸蝕完成后,5組試件分別涂布去離子水(對照組)和CPP-ACP、CPP-ACPF、TCP+F、Duraphat進行再礦化處理,隨后繼續(xù)酸蝕處理5 d。采用顯微硬度法測量處理前后各組試件的表面硬度(顯微硬度值),掃描電子顯微鏡(掃描電鏡)觀察牙釉質表面形態(tài)的變化。結果酸蝕處理前5組試件顯微硬度值的差異無統(tǒng)計學意義(P0.05);酸蝕處理后各組試件的顯微硬度值均顯著低于酸蝕處理前(P0.05),但各組間比較差異無統(tǒng)計學意義(P0.05);分組處理繼續(xù)酸蝕5 d后,CPP-ACP組、CPP-ACPF組、TCP+F組和Duraphat組試件的顯微硬度值均顯著高于對照組(P0.05),但4組間的差異無統(tǒng)計學意義(P0.05)。掃描電鏡觀察發(fā)現(xiàn),分組處理繼續(xù)酸蝕5 d后,除對照組試件外,其余4組牙釉質塊試件均可見礦物質沉積。結論再礦化制劑CPP-ACP、CPP-ACPF、TCP+F和Duraphat均能有效抑制酸蝕乳牙釉質的持續(xù)脫礦。
[Abstract]:Objective to observe the surface hardness of casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP), fluorine-containing casein phosphate-amorphous calcium phosphate complex (CPP-ACPF), tricalcium phosphate (TCP F) and Duraphat protective paint on the enamel surface of acid-etched milk. The effect of surface morphology. Methods 50 specimens of enamel mass (hardness of 280 ~ 330 HV) were prepared from the central incisor of mandibular milk after extraction and were randomly divided into three groups: control group, CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group. All the specimens (Coca-Cola, 5 times / dl, 5 min/) were treated with deionized water (control group) and CPP-ACP,CPP-ACPF,TCP FU Duraphat for 5 d), after the etching was completed, and then the treatment was continued for 5 days. The surface hardness (microhardness) of each group of specimens before and after treatment was measured by microhardness method, and the changes of enamel surface morphology were observed by scanning electron microscope (SEM). Results there was no significant difference in microhardness values between the five groups before acid etching treatment (P0.05), and the microhardness values of each group after acid etching treatment were significantly lower than those before acid etching treatment (P0.05), but there was no significant difference among the groups (P0.05). After continuous etching for 5 days, the microhardness of CPP-ACP group, CPP-ACPF group, TCP F group and Duraphat group were significantly higher than that of control group (P0.05), but there was no significant difference among the four groups (P0.05). Scanning electron microscopy (SEM) showed that mineral deposits were observed in the enamel samples of the other 4 groups except the control group after 5 days of treatment. Conclusion both CPP-ACP,CPP-ACPF,TCP F and Duraphat can effectively inhibit the continuous demineralization of enamel.
【作者單位】： 口腔疾病與生物醫(yī)學重慶市重點實驗室重慶醫(yī)科大學附屬口腔醫(yī)院兒童口腔科;
【基金】：重慶市衛(wèi)生局2012年醫(yī)學科研計劃項目(2012-2-126) 重慶市教委科學技術研究項目(kj120329)~~
【分類號】：R781.2

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