【摘要】：目的:通過(guò)觀察慢性牙周炎患者行牙種植修復(fù)后一年內(nèi)的臨床效果及IL-1及IL-6的水平的變化,探討慢性牙周炎和種植體周圍炎的相關(guān)性,為慢性牙周炎患者種植修復(fù)提供理論基礎(chǔ)。方法:隨機(jī)選擇18例慢性牙周炎患者的28顆種植牙為A組,15例牙周健康者的20顆種植牙為B組,對(duì)A、B兩組種植牙修復(fù)后1、3、6、12個(gè)月檢測(cè)種植牙的改良菌斑指數(shù)(m PLI)、改良齦溝出血指數(shù)(m SBI)、探診深度(PD)及邊緣骨吸收(MBL)量,采用ELISA法檢測(cè)齦溝液中IL-1β和IL-6的含量,同時(shí)記錄種植修復(fù)后一年種植體的存留率。采用SPSS17.0統(tǒng)計(jì)軟件包對(duì)實(shí)驗(yàn)相關(guān)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:一年內(nèi)兩組種植體存留率100%。橫向比較結(jié)果:1.慢性牙周炎組和牙周健康組的m PLI,MBL、IL-6的含量在種植修復(fù)后3個(gè)月時(shí)開(kāi)始差異有統(tǒng)計(jì)學(xué)意義。而兩組的m SBI和PD在種植修復(fù)后1個(gè)月和3個(gè)月差異無(wú)統(tǒng)計(jì)學(xué)意義,6個(gè)月開(kāi)始差異有統(tǒng)計(jì)學(xué)意義�？v向比較結(jié)果:1.兩組的改良菌斑指數(shù)(m PLI)差別無(wú)統(tǒng)計(jì)學(xué)意義,改變幅度相同。2.兩組IL-1β的含量差別有統(tǒng)計(jì)學(xué)意義,改變幅度相同。3.種植修復(fù)后3個(gè)月開(kāi)始,慢性牙周炎組種植體齦溝液中IL-6含量的改變幅度大于牙周健康組4.兩組m SBI、MBL、PD在種植修復(fù)后6個(gè)月開(kāi)始差異有統(tǒng)計(jì)學(xué)意義,且慢性牙周炎組改變幅度大于牙周健康組。結(jié)論:1.慢性牙周炎牙列缺損種植修復(fù)短期內(nèi)可以獲得良好的臨床療效。2.慢性牙周炎種植患者羈患種植體周圍炎的風(fēng)險(xiǎn)更大,行種植義齒修復(fù)需謹(jǐn)慎!3.種植義齒修復(fù)后尤其是慢性牙周炎種植患者早期就應(yīng)注重種植義齒的清潔維護(hù),有助于提高種植義齒的遠(yuǎn)期成功率
[Abstract]:Objective: to investigate the correlation between chronic periodontitis and peri-implant periodontitis by observing the clinical effect and the changes of IL-1 and IL-6 in patients with chronic periodontitis within one year after dental implant repair. To provide a theoretical basis for implant repair in patients with chronic periodontitis. Methods: Twenty-eight implants of 18 patients with chronic periodontitis were randomly selected as group A and 20 implants of 15 healthy people as group B. The modified plaque index (m PLI), modified gingival sulcus bleeding index (m SBI), probing depth (PD) and marginal bone resorption (MBL) were detected at 12 months after implant restoration in group A and B, and the contents of IL-1 尾 and IL-6 in gingival crevicular fluid were detected by ELISA method. At the same time, the survival rate of implant was recorded one year after implant restoration. The experimental data were analyzed by SPSS17.0 software package. Results: the survival rate of implants in two groups was 100% within one year. Horizontal comparison: 1. The content of m PLI,MBL,IL-6 in chronic periodontitis group and periodontal health group was significantly different 3 months after implant repair. However, there was no significant difference in m SBI and PD between the two groups at 1 month and 3 months after implant repair, but there was a significant difference between the two groups at the beginning of 6 months. Vertical comparison: 1. There was no significant difference in improved plaque index (m PLI) between the two groups. The difference of IL-1 尾 content between the two groups was statistically significant, the range of change was the same. 3. 3. The change of IL-6 content in gingival crevicular fluid in chronic periodontitis group was greater than that in healthy periodontal group 3 months after implantation. There was significant difference in m SBI,MBL,PD between the two groups at the beginning of 6 months after implant repair, and the change of m SBI,MBL,PD in chronic periodontitis group was larger than that in healthy periodontal group. Conclusion 1. In the short term, the implant repair of chronic periodontitis dentition defect can obtain good clinical effect. 2. 2. Patients with chronic periodontitis are at greater risk of peri-implant inflammation. In order to improve the long-term success rate of implant denture, especially in patients with chronic periodontitis, the clean maintenance of implant denture should be paid attention to in the early stage after the restoration of implant denture, especially in patients with chronic periodontitis.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R781.42

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