本文選題：上皮間質(zhì)轉(zhuǎn)化 + TGF-β��； 參考：《實用口腔醫(yī)學雜志》2014年02期

【摘要】：通過免疫組化(SP法)技術(shù)檢測54例口腔癌中E-cadherin、Vimentin及TGF-β1的表達,結(jié)果顯示E-cadherin、Vimentin及TGF-β1表達陽性率分別為55.6%、33.33%、59.3%,與正�？谇火つは啾炔町愑酗@著性(P0.05);TGF-β1表達不僅與淋巴結(jié)轉(zhuǎn)移密切相關(guān),且與Vimentin表達呈顯著正相關(guān)關(guān)系�？谇话┛赏ㄟ^上皮間質(zhì)轉(zhuǎn)化EMT促進侵襲轉(zhuǎn)移,TGF-β1促進EMT進程。
[Abstract]:The expression of Vimentin and TGF- 尾 1 in 54 cases of oral carcinoma was detected by immunohistochemistry (SP method). The results showed that the positive rates of E-cadherinon vimentin and TGF- 尾 1 were 55.6% and 33.3333% respectively. The expression of TGF- 尾 1 was not only closely related to lymph node metastasis, but also significantly different from that of normal oral mucosa. There was a significant positive correlation between Vimentin expression and Vimentin expression. Oral carcinoma can promote invasion and metastasis by transforming EMT into epithelium. TGF- 尾 1 can promote EMT process.
【作者單位】： 濱州醫(yī)學院病理學教研室;濱州醫(yī)學院影像學教研室;
【分類號】：R739.85

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相關(guān)期刊論文 前2條

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本文編號：2080232