本文選題：復發(fā)性阿弗他潰瘍 + 口腔健康相關生活質量　； 參考：《大連醫(yī)科大學》2017年碩士論文

【摘要】：研究目的:通過口腔健康影響程度量表(OHIP-14中文版)評估復發(fā)性阿弗他潰瘍(RAU)患者的口腔健康相關生活質量(oral health related quality of life,OHRQOL),并通過焦慮自評量表(SAS)、抑郁自評量表(SDS)、疼痛度視覺類比標尺值(VAS值)及OHIP-14評估RAU患者OHRQOL與其心理健康狀況之間的相關性。通過對數(shù)據(jù)的研究,給RAU的病因及發(fā)病機制作理論支持,以期優(yōu)化RAU的療效,給臨床治療提供強有力的支持。研究方法:選取于大連醫(yī)科大學附屬第一醫(yī)院口腔門診就診的111例RAU病人作為RAU組,再選取在年齡、性別、文化水平等方面相仿的100例非RAU個人作為對照組。使用OHIP-14、SAS、SDS對111例RAU患者及100例非RAU對照組人群作調查,同時寫下RAU患者的VAS值、潰瘍個數(shù)與位置,隨后收回調查問卷,再對調查問卷的有效性作以評估。在處理最終數(shù)據(jù)時選擇SPSS 22.0軟件。研究結果:1.被調查的111例RAU患者中,性別為女的有77例(69.4%),性別為男的有34例(30.6%),女性明顯多于男性;年齡15～75歲,平均年齡38.3±14.4歲,其中15～30歲有39例,30～45歲有36例,45～60歲有27例,60～75歲有9例;輕型復發(fā)性阿弗他潰瘍(MiRAU)86例,腺周口瘡(MaRAU)11例,口炎型口瘡(HU)14例;潰瘍發(fā)生的位置在舌部占38.3%,唇部占25.5%,牙齦占14.9%,頰部占12.3%,口底黏膜占5.0%,硬腭占4.0%;有明顯家族遺傳傾向的有12例;與月經周期有關的有13例;戒煙后加重的有3例。2.被調查的111例RAU患者和對照組的0HIP-14總得分的中位數(shù)分別是22和10,RAU組明顯高于對照組,而且在功能限制、生理性疼痛、生理障礙、心理障礙這4個領域也較對照組差異明顯。3.RAU患者OHIP-14各條目中表現(xiàn)為負面影響的個體所占比例中除了功能限制、生理性疼痛、生理障礙、心理障礙四個領域差異明顯外,在"覺得生活不是那么令人滿意"方面的個體所占比例也比對照組高,差異較大。4.RAU患者的OHRQOL越差,疼痛便會隨之增加,焦慮和抑郁的癥狀也隨之加重;RAU患者的OHIP-14總得分與VAS分值、SAS分值、SDS分值均呈正相關。研究結論:1.RAU對患者的OHRQOL有著消極的影響。2.RAU患者的OHRQOL與VAS分值、SAS分值、SDS分值呈正相關。因此應該首先解決RAU造成的口腔功能障礙問題,然后有所側重地關注患者的心理、工作、社會環(huán)境對疾病的干擾,使生理、心理治療相結合,提高患者的心理健康程度,釋放壓力,從而改善RAU病人的生活質量。
[Abstract]:Objective: to evaluate the oral health related quality of life (QOL) in patients with recurrent aphthous ulcer (Rau) by OHIP-14), and to evaluate the quality of oral health related quality of life (QOL) in patients with recurrent aphthous ulcer.Visual analogies (VAS) and OHIP-14 were used to evaluate the correlation between OHRQOL and mental health in patients with RAU.In order to optimize the curative effect of RAU and provide strong support for clinical treatment, the study of data provides theoretical support for the etiology and pathogenesis of RAU.Methods: one hundred and eleven patients with RAU were selected as RAU group in the oral clinic of the first affiliated Hospital of Dalian Medical University, and 100 non- patients with similar age, sex and education level were selected as the control group.Using OHIP-14 sasco SDS to investigate 111 cases of RAU and 100 cases of non- control group. At the same time, write down the VAS value, the number and location of ulcers in RAU patients, and then withdraw the questionnaire, and then evaluate the effectiveness of the questionnaire.Select SPSS 22. 0 software when processing final data.The result of the study was: 1.Among the 111 RAU patients investigated, 77 cases were female, 34 cases were male, the age was 1575 years old, the average age was 38.3 鹵14.4 years old, 39 cases were 1530 years old, 36 cases were 4560 years old, 27 cases were 6060 years old, 9 cases were 75 years old, the age was 1575 years old with an average age of 38.3 鹵14.4 years.There were 86 cases of mild recurrent aphthous ulcer with MiRAUU, 11 cases with periglandular aphthous ulcer and 14 cases with stomatitis type of stomatitis, the location of ulcer was 38.3% in the tongue, 25.5% in the lip, 14.9% in the gingiva, 12.3 in the buccal part, 5.0 in the fundus mucosa and 4.0 in the hard palate. 12 cases had obvious familial genetic tendency.There were 13 cases associated with menstrual cycle and 3 cases aggravated after quitting smoking.The median of total 0HIP-14 scores of 111 RAU patients and control group were 22 and 10, respectively, which were significantly higher than those in the control group, and were significantly higher than those in the control group in terms of functional limitation, physiological pain, and physiological disorders.Compared with the control group, there were significant differences in the proportion of individuals with negative effects in the OHIP-14 of patients with Rau, except for functional limitation, physiological pain, physiological disorder and psychological disorder, among which there were significant differences in the four areas, including functional limitation, physiologic pain, physiological disorder and psychological disorder.The proportion of individuals who "felt less satisfied with life" was also higher than that in the control group. 4. The worse the OHRQOL of patients with Rau, the higher the pain.The symptoms of anxiety and depression also aggravated. The total score of OHIP-14 was positively correlated with the score of VAS.Conclusions 1. Rau has a negative effect on the OHRQOL of patients. 2. There is a positive correlation between OHRQOL and VAS scores in patients with Rau.Therefore, we should first solve the problem of oral dysfunction caused by RAU, and then pay more attention to the disturbance of patients' psychology, work and social environment to the disease, so as to combine physiology and psychotherapy to improve the patients' mental health.Release pressure to improve the quality of life of RAU patients.
【學位授予單位】：大連醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R781.5
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本文編號：1764760