本文選題：牙酸蝕癥 + 新消感��； 參考：《山東大學》2014年碩士論文

【摘要】：1、通過體外實驗,研究新消感預防果汁引起的牙釉質(zhì)脫礦。為酸蝕癥的預防提供實驗依據(jù)。 2、通過體外實驗,研究新消感治療果汁引起的牙釉質(zhì)脫礦,不同濃度的新消感對硬度改變的影響。為酸蝕癥的治療及臨床上使用新消感提供實驗據(jù)。 收集口腔外科拔除的牙冠完整的新鮮上頜第三磨牙40顆,制成牙釉質(zhì)樣本,分為兩組實驗：①新消感對預防牙齒酸蝕癥的體外實驗研究：取30個牙釉質(zhì)樣本,隨機分三組(對照組、果汁飲料組、果汁飲料+新消感組)。處理7天后于掃描電鏡觀察各組牙齒牙釉質(zhì)表面的形態(tài)學變化。②新消感對治療牙齒酸蝕癥的體外實驗研究：另選取50個牙釉質(zhì)樣本,隨機分5組(對照組、25%新消感組、50%新消感組、75%新消感組、100%新消感組),果汁酸蝕7天,然后用不同濃度新消感處理7天,分別測量再礦化實驗前后各組樣本牙釉質(zhì)表面顯微硬度。 1、新消感預防牙齒酸蝕癥實驗的掃描電鏡觀察結果： 酸蝕后牙釉質(zhì)表面形態(tài)不規(guī)則,呈凸凹不平的粗糙面。新消感加橙汁處理后,散在的凹陷性缺損,表面伴有大量的分布不均勻礦物質(zhì)顆粒沉積,成塊狀、片狀的沉積物覆蓋在釉質(zhì)表面的凹陷窩內(nèi),使脫礦區(qū)的深度變淺。 2、新消感治療牙齒酸蝕癥實驗的牙釉質(zhì)表面顯微硬度測試結果： 再礦化后的對照組(蒸餾水組)及25%新消感組的牙釉質(zhì)表面顯微硬度較再礦化前均無明顯上升,差異無統(tǒng)計學意義(P0.05)；50%新消感組、75%新消感組、100%新消感組經(jīng)再礦化處理后,3組牙釉質(zhì)表面顯微硬度均較再礦化前明顯上升,差異有統(tǒng)計學意義(P0.05)。 對照組(蒸餾水組)與25%新消感組、50%新消感組與75%新消感組、50%新消感組與100%新消感組、75%新消感組與100%新消感組每兩組間的再礦化后的牙釉質(zhì)表面顯微硬度差異無統(tǒng)計學意義(P0.05)；對照組(蒸餾水組)分別與50%新消感組、75%新消感組、100%新消感組的再礦化后的牙釉質(zhì)表面顯微硬度差異均有統(tǒng)計學意義(P0.05)。25%新消感組分別與50%新消感組、75%新消感組、100%新消感組的再礦化后的牙釉質(zhì)表面顯微硬度差異均有統(tǒng)計學意義(P0.05)。 [實驗結論] 新消感對牙齒酸蝕癥的發(fā)展有抑制作用。 新消感對已經(jīng)形成酸蝕癥的牙齒有促進再礦化的作用,其作用與濃度有關：25%的新消感對酸蝕癥的牙齒無再礦化的作用；50%、75%、100%的新消感對酸蝕癥的牙齒均有促進其再礦化的作用。
[Abstract]:1. Through in vitro experiments, the prevention of tooth enamel demineralization caused by juice was studied.To provide experimental basis for the prevention of acidosis.2. Through in vitro experiments, the effects of different concentrations of new desensitization on the hardness of tooth enamel induced by juice were studied.To provide experimental evidence for the treatment of acidosis and clinical use of new Xiaoxiang.A total of 40 fresh maxillary third molars with intact crown extracted by oral surgery were collected and made into enamel samples, which were divided into two groups: 30 enamel samples were collected to prevent tooth acidosis.The rats were randomly divided into three groups (control group, juice drink group, juice drink Xinxiao group).After 7 days of treatment, the morphological changes of enamel surface in each group were observed by scanning electron microscope.They were randomly divided into 5 groups (control group, 25% Xinxiao group, 50% Xinxiaoxen group, 75% Xinxian group, 100% Xinxiao group, 7 days fruit juice acid etching, and then treated with different concentrations of new elimination sensation for 7 days, respectively). The surface microhardness of enamel in each group was measured before and after the remineralization experiment.1. The results of scanning electron microscope (SEM) observation on the prevention of dental acidosis by Xinxiaoxen:The surface of enamel was irregular and rough after acid etching.After the treatment of Xinxiaogan and orange juice, the scattered sunken defect, accompanied by a large amount of uneven distribution of mineral particles deposition, block, sheet sediment covered in the lacuna of enamel surface, make the depth of demineralization shallower.2.The microhardness of enamel surface in the treatment of tooth acidosis:The surface microhardness of enamel in the control group (distilled water group) and 25% Xinxiao group after remineralization showed no significant increase compared with that before remineralization.There was no significant difference in the surface microhardness of enamel between the three groups (P 0.05%, P 0.05%, P 0.05), and the surface microhardness of tooth enamel in group C (P 0.05) was significantly higher than that in group C (P 0.05) after the treatment of remineralization, and the surface microhardness of enamel in group C was significantly higher than that in group C (P 0.05).Control group (distilled water group), 25% Xinxiao group, 50% Xinxian group and 75% Xinxiaoxen group, 50% Xinxian group and 100% Xinxiaoxen group, 75% Xinxiaoxen group and 100% Xinxiaoxen group have no difference in the surface microhardness of enamel after re-mineralization between each two groups, and there is no difference in the microhardness of enamel surface between each of the two groups.There were significant differences in surface microhardness of enamel between the control group (distilled water group) and 50% Xinxiao group (75% Xinxiao group, 100% Xinxiao group) and 50% Xinxiao group (P 0.05% .25% Xinxiao group respectively), while the surface microhardness of enamel surface in the control group (distilled water group) was significantly different from that in the 50% Xinxiao group (100% Xinxiao group).There were significant differences in the surface microhardness of enamel of 75% Xinxiao group (100% XXG) and 100% XXG group (P 0.05).[experimental conclusions]The development of tooth acidosis can be inhibited by new Xiaogan.The effect of Xinxiao on the teeth that have already formed acidosis is related to the concentration. The effect of Xinxiao of 25% on the non-mineralization of the teeth of acidosis. 50% of Xinxiao has the effect of promoting the remineralization of the teeth of acidosis.
【學位授予單位】：山東大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R781

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本文編號：1749865