本文選題：復發(fā)性阿弗他潰瘍　切入點：康復新液　出處：《中國藥房》2016年08期 　論文類型：期刊論文

【摘要】：目的:探討康復新液聯(lián)合口腔潰瘍散對復發(fā)性阿弗他潰瘍患者炎性因子及療效的影響。方法:134例復發(fā)性阿弗他潰瘍患者采用隨機數字表法分為觀察組和對照組,各67例。兩組患者均給予常規(guī)治療,對照組患者在此基礎上加用口腔潰瘍散噴灑于口腔潰瘍處,q2 h;觀察組患者在對照組基礎上加用康復新液,每次10 ml,口中含漱5~10 min后緩慢咽下,tid。兩組療程均為7 d。觀察兩組患者的臨床療效、炎性因子指標、臨床癥狀改善程度及復發(fā)情況。結果:觀察組患者的總有效率為95.52%,明顯高于對照組(82.09%),差異具有統(tǒng)計學意義(P0.05)。觀察組患者的腫瘤壞死因子α、白細胞介素(IL)-1、IL-6水平均顯著低于對照組,差異具有統(tǒng)計學意義(P0.05);觀察組患者的潰瘍持續(xù)時間顯著短于對照組,視覺模擬評分法評分顯著低于對照組,差異均具有統(tǒng)計學意義(P0.05)。隨訪6個月,觀察組患者的復發(fā)率(11.94%)明顯低于對照組(31.34%),差異具有統(tǒng)計學意義(P0.05)。結論:康復新液聯(lián)合口腔潰瘍散有助于降低復發(fā)性阿弗他潰瘍患者的炎性因子水平,緩解臨床癥狀,提高療效,降低復發(fā)率。
[Abstract]:Objective: to investigate the effect of Kangangxin liquid combined with oral ulcer powder on inflammatory factors and curative effect in patients with recurrent aphthous ulcer. Methods: 134 patients with recurrent aphthous ulcer were randomly divided into two groups: observation group and control group. 67 patients in each group were given routine treatment, and the patients in the control group were sprayed with oral ulcer powder for Q2 h, and the patients in the observation group were treated with new rehabilitation solution on the basis of the control group. 10 ml / time, 5 min after mouth gargling, 10 min after slow swallow tid. The course of treatment in both groups was 7 days. The clinical curative effect and inflammatory factor index were observed in both groups. Results: the total effective rate of the patients in the observation group was 95.522.The total effective rate was significantly higher than that in the control group (P 0.05). The levels of tumor necrosis factor 偽 and interleukin-1 IL-6 in the observation group were significantly lower than those in the control group. The duration of ulcers in the observation group was significantly shorter than that in the control group, and the visual analogue score was significantly lower than that in the control group (P 0.05). The recurrence rate of the patients in the observation group was significantly lower than that in the control group (P 0.05). Conclusion: the level of inflammatory factors in patients with recurrent aphthous ulcer can be reduced, the clinical symptoms can be alleviated and the curative effect improved. Reduce the recurrence rate.
【作者單位】： 華中科技大學同濟醫(yī)學院附屬協(xié)和醫(yī)院口腔科;武漢市第一醫(yī)院口腔科;華中科技大學同濟醫(yī)學院附屬協(xié)和醫(yī)院藥劑科;
【分類號】：R781.5
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本文編號：1644256