本文選題：激光成型鈷鉻合金　切入點(diǎn)：變形鏈球菌　出處：《南昌大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：選擇性激光成型鈷鉻合金的物理性能、機(jī)械性能等方面經(jīng)證實(shí)均優(yōu)于或等同于臨床鑄造鈷鉻合金。但長期進(jìn)駐口腔環(huán)境時，鈷鉻合金修復(fù)體的表面會有細(xì)菌粘附聚集，甚至引起某些口腔疾病。 目的： 評價在模擬口腔環(huán)境下，測試選擇性激光成型鈷鉻合金與Wirobond280鈷鉻合金、SG鈷鉻合金的表面自由能以及變形鏈球菌在試件表面的粘附情況，進(jìn)而為選擇性激光加工合金修復(fù)體用于臨床提供基礎(chǔ)資料。 材料和方法： 材料：三組大小一致的鈷鉻合金試件：1）A組-鑄造SG鈷鉻合金試件：Co63.9%Cr24.7%Mo5%W5.4%Si1%（BEGO公司，，Wirocast S，德國）。2）B-組鑄造Wirobond280鈷鉻合金試件：Co60.2%Cr25%Mo4.8%W6.2%Ga2.9%)（BEGO公司，Wirocast S，德國）。3）C組-激光成型鈷鉻合金試件：Co60.5%Cr28%Mo5%W9%Si1.5%（BEGO公司，Wirocast S，德國）。方法：ABC三組試件包埋后分別使用SiC砂紙逐級打磨試件表面至具有相同表面粗糙度（Ra）(0.32-0.33ｕm)值范圍，然后使用環(huán)境掃描顯微鏡與光學(xué)接觸角測量儀（德國KRUSS DSA100）分別測試ABC三組試件的表面形態(tài)與表面接觸角；ABC試件分別置于PH6.8的無菌人工唾液中浸泡24小時。24小時候后將ABC置于含有變形鏈球菌（Ua159）的MRS液體培養(yǎng)基中厭放于氧環(huán)境下培養(yǎng)48小時，最后定量檢測三組試件表面粘附的細(xì)菌數(shù)量。 結(jié)果： （1）對于三組鈷鉻合金材料在相同粗糙度下所測得的表面接觸角值進(jìn)行單因素方差分析結(jié)果顯示：三組鈷鉻合金試件的表面接觸角無統(tǒng)計(jì)學(xué)意義（P0.05）。 （2）相同培養(yǎng)條件下，對三組試件表面粘附的變形鏈球菌計(jì)數(shù)所得數(shù)據(jù)進(jìn)行單因素方差分析結(jié)果顯示：三組不同方式加工的鈷鉻合金試件表面粘附的變形鏈球菌量無統(tǒng)計(jì)學(xué)意義（P0.05）。 結(jié)論： 通過本實(shí)驗(yàn)研究結(jié)果顯示： （1）表面粗糙度相同的前提下，激光成型鈷鉻合金的表面自由能與Wirobond280鈷鉻合金和SG鈷鉻合金表面自由能相似。 （2）表面粗糙度相同的前提下，變形鏈球菌在三組試件表面的粘附情況相似。
[Abstract]:The physical and mechanical properties of selective laser molding cobalt-chromium alloy have been proved to be superior to or equal to that of clinical cast cobalt-chromium alloy. However, bacterial adhesion and aggregation will occur on the surface of cobalt-chromium alloy prosthesis when it is in oral environment for a long time. It even causes some oral diseases. Objective:. To evaluate the surface free energy of selective laser molded cobalt-chromium alloy and Wirobond280 cobalt-chromium alloy SG cobalt-chromium alloy and the adhesion of Streptococcus mutans on the surface of the specimen in simulated oral environment. It provides basic data for clinical application of selective laser processing of alloy restorations. Materials and methods:. Materials: three groups of Co Cr alloy specimens of the same size: group A: casting SG Cobalt Chromium Alloy specimen: cast Co. 63.9Cr24.7Mo5W5.4Si1c. Including W24.7Mo5W5.4Si1and BEGO W60.2Cr252Cr252Cr25Cr25Mo4.8W6.2Ga2.2Ga2.2W6.2Ga2.2BO, Group C, Germany, Group C-Laser forming Cobalt-Chromium Alloy Test piece: Co60.5Cr28Mo5W9Si1.5BEGO Group C-Laser forming Cobalt-Chromium Alloy Test piece: Co60.5Cr28Mo5W9Si1.5BEGO. Methods after embedding three groups of specimens, SiC sandpaper was used to grind the surface of the specimens to the range of 0.32-0.33 umum with the same surface roughness. Then the surface morphology and surface contact angle of the three groups of ABC specimens were measured by environmental scanning microscope and optical contact angle measuring instrument (KRUSS DSA100, Germany). The samples were immersed in the sterile artificial saliva of PH6.8 for 24 hours and 24 hours, respectively. ABC was then cultured in MRS liquid medium containing Streptococcus mutans Ua159 for 48 hours. Finally, the number of bacteria adhered to the surface of the three groups of specimens was determined quantitatively. Results:. 1) the results of single factor ANOVA analysis on the surface contact angle of three groups of cobalt-chromium alloy materials under the same roughness show that the surface contact angle of the three groups of cobalt-chromium alloy specimens has no statistical significance (P 0.05). (2) under the same culture condition, the single factor analysis of variance showed that the amount of streptococcus mutans adhered to the surface of three groups of cobalt-chromium alloy specimens processed in different ways had no statistical significance (P 0.05). Conclusion:. The experimental results show that:. On the premise of the same surface roughness, the surface free energy of laser-formed cobalt-chromium alloy is similar to that of Wirobond280 cobalt-chromium alloy and SG cobalt-chromium alloy. When the surface roughness is the same, the adhesion of Streptococcus mutans on the surface of three groups of specimens is similar.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R783.1

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