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缺血性腦白質(zhì)病變與認(rèn)知功能障礙的相關(guān)性研究

發(fā)布時(shí)間:2018-10-11 12:13
【摘要】:目的探缺血性腦白質(zhì)病變與認(rèn)知障礙的關(guān)系,為血管性癡呆的預(yù)防、早期診斷和治療提供理論依據(jù)。方法選擇138例經(jīng)顱腦MRI證實(shí)的腦白質(zhì)病變患者,并分為缺血性腦白質(zhì)病變組和非缺血性腦白質(zhì)病變組,分別進(jìn)行簡(jiǎn)易智能狀態(tài)檢查量表(MMSE)評(píng)估比較,并對(duì)白質(zhì)病變進(jìn)行分級(jí),進(jìn)行組內(nèi)及兩組患者認(rèn)知功能?chē)?yán)重程度比較。結(jié)果缺血性白質(zhì)病變組認(rèn)知功能障礙發(fā)生率及Ⅱ、Ⅲ段白質(zhì)病變者的認(rèn)識(shí)功能障礙的嚴(yán)重程度明顯高于非缺血性白質(zhì)病變組;組內(nèi)比較缺血性白質(zhì)病變組和非缺血性白質(zhì)病變組認(rèn)知功能障礙與白質(zhì)病變嚴(yán)重分級(jí)呈正相關(guān),而二者無(wú)明顯關(guān)系。結(jié)論缺血性白質(zhì)病及其嚴(yán)重程度對(duì)認(rèn)知功能障礙的發(fā)生及嚴(yán)重程度有顯著影響,而非缺血性白質(zhì)病則對(duì)認(rèn)知功能障礙影響較小。
[Abstract]:Objective to explore the relationship between ischemic white matter lesions and cognitive impairment, and to provide theoretical basis for the prevention, early diagnosis and treatment of vascular dementia. Methods one hundred and eight patients with cerebral white matter disease confirmed by brain MRI were divided into ischemic and non-ischemic white matter disease groups. (MMSE) was used to evaluate and compare the simple Intelligent State Checklist, and the white matter lesions were classified. To compare the severity of cognitive function between the group and the two groups. Results the incidence of cognitive dysfunction and the severity of cognitive dysfunction in patients with 鈪,

本文編號(hào):2264149

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