天津薊縣農(nóng)村地區(qū)老年人代謝及認(rèn)知功能調(diào)查
發(fā)布時(shí)間：2018-10-11 11:50
【摘要】：目的 通過(guò)對(duì)天津市薊縣農(nóng)村地區(qū)1268名60歲及以上的老年人認(rèn)知功能的調(diào)查,研究家族史、個(gè)人史、及身高、體重、腰圍(WC)、血壓、心率等一般情況,及空腹血糖、甘油三酯(TG)、膽固醇(TC)等因素與認(rèn)知功能障礙之間的關(guān)系,探討天津農(nóng)村地區(qū)老年人認(rèn)知功能的特征,為提高農(nóng)村地區(qū)認(rèn)知功能障礙的知曉率和診斷率、治療率提供依據(jù)。 方法 采用篩查法進(jìn)行調(diào)查,收集性別、年齡、教育程度、個(gè)人高血壓及冠心病史、飲酒、飲茶史等基本信息；測(cè)量身高、體重、WC、血壓、心率；測(cè)定甘油三酯、膽固醇、空腹血糖水平；并行簡(jiǎn)易智能狀態(tài)檢查量表(mini-mental state examination,MMSE)評(píng)估認(rèn)知功能,以MMSE分?jǐn)?shù)文盲組17分,小學(xué)組22分,初中及以上組26分標(biāo)準(zhǔn)考慮認(rèn)知功能受損,將調(diào)查人群分為MMSE分?jǐn)?shù)正常組(700人),MMSE分?jǐn)?shù)異常組(568人),比較兩組年齡、性別、受教育年限、身高、體重、體重指數(shù)、WC、血壓、心率、血糖、甘油三酯、膽固醇、及家族史和飲酒等生活習(xí)慣的差異。將調(diào)查對(duì)象按WC、體重指數(shù)、血壓、血糖、膽固醇、甘油三酯數(shù)值正常與否進(jìn)行分類,探討代謝因素對(duì)認(rèn)知狀況的影響。將調(diào)查對(duì)象按不同年齡段分組,探討年齡對(duì)于認(rèn)知能力的影響。進(jìn)行MMSE各亞項(xiàng)分析,探討農(nóng)村地區(qū)人群認(rèn)知各亞項(xiàng)損害范圍及損害程度。 結(jié)果 MMSE正常組較MMSE異常組男性比例高、WC長(zhǎng)、舒張壓高,差異有明顯統(tǒng)計(jì)學(xué)意義(P0.05),MMSE正常組較MMSE異常組年齡輕、受教育年限高、有吸煙史比例高,差異有統(tǒng)計(jì)學(xué)意義(P0.01)。收縮壓低、舒張壓高、空腹血糖及膽固醇水平正常人群的MMSE分?jǐn)?shù)較高,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。WC、舒張壓與MMSE分?jǐn)?shù)呈顯著正相關(guān)；收縮壓、心率、空腹血糖、膽固醇與MMSE分?jǐn)?shù)呈負(fù)相關(guān)(P0.05)。MMSE分?jǐn)?shù)隨年齡組升高呈下降趨勢(shì),年齡組越高人群MMSE分?jǐn)?shù)低于正常值比例越大。全體調(diào)查對(duì)象的MMSE亞項(xiàng)評(píng)分均顯著低于相應(yīng)亞項(xiàng)總分(P0.01),其中亞項(xiàng)評(píng)分低于亞項(xiàng)總分例數(shù)最多的三項(xiàng)是：記憶力(91.64%)、注意力和計(jì)算力(74.84%)、定向力(70.27%)。較亞項(xiàng)總分下降幅度最大的三項(xiàng)是：記憶力(73.3%)、閱讀能力(53%)、書寫(47%)、結(jié)構(gòu)能力(47%)。 結(jié)論 農(nóng)村地區(qū)老年人認(rèn)知狀態(tài)與性別、年齡、教育年限、吸煙史、WC等相關(guān)；同時(shí),體重、空腹血糖、膽固醇等代謝異常也與認(rèn)知能力受損程度密切相關(guān)。農(nóng)村地區(qū)老年人認(rèn)知能力損害較廣泛,其中記憶力、注意力和計(jì)算力、閱讀、書寫能力等認(rèn)知能力亞項(xiàng)損害尤為嚴(yán)重。MMSE量表部分亞項(xiàng)測(cè)試方式適用于農(nóng)村地區(qū)尚需調(diào)整。農(nóng)村地區(qū)老年人認(rèn)知狀態(tài)不容樂觀,農(nóng)村地區(qū)老年人對(duì)于阿爾茨海默病(AD)的認(rèn)識(shí)不足,農(nóng)村地區(qū)老年人的認(rèn)知狀態(tài)需要得到更多關(guān)注。
[Abstract]:Objective to study the family history, personal history, height, weight, waist circumference, (WC), blood pressure, heart rate and fasting blood glucose in 1268 elderly people aged 60 years or over in Jixian rural area of Tianjin, and to study the family history, personal history, height, weight, waist circumference, blood pressure, heart rate and so on. The relationship between triglyceride (TG), cholesterol (TC) and cognitive dysfunction was studied. The characteristics of cognitive function of the elderly in rural areas of Tianjin were studied in order to provide evidence for improving the rate of awareness, diagnosis and treatment of cognitive dysfunction in rural areas. Methods basic information such as sex, age, education, history of hypertension and coronary heart disease, drinking and drinking tea were collected, height, weight, WC, blood pressure, heart rate, triglyceride were measured. Cholesterol, fasting blood glucose level, cognitive function were assessed with the simple Mental State Checklist (mini-mental state examination,MMSE). Cognitive impairment was assessed by MMSE scores of 17 in illiterate group, 22 in primary school group, and 26 in junior high school and above group. The subjects were divided into normal MMSE score group (700 patients with abnormal), MMSE score). Age, sex, years of education, height, body mass index, WC, blood pressure, heart rate, blood glucose, triglyceride, cholesterol were compared between the two groups. And differences in family history and drinking habits. The subjects were classified according to WC, body mass index, blood pressure, blood glucose, cholesterol and triglyceride values, and the effects of metabolic factors on cognitive status were investigated. The subjects were divided into different age groups to explore the effect of age on cognitive ability. The subitems of MMSE were analyzed to explore the extent and extent of cognitive impairment in rural population. Results the proportion of male, WC and diastolic blood pressure in MMSE normal group were higher than those in MMSE abnormal group, and the difference was statistically significant (P0.05). (P0.05), MMSE normal group was younger than that of MMSE abnormal group, higher education years and higher proportion of smoking history (P0.01). Systolic blood pressure was low, diastolic blood pressure was high, fasting blood glucose and cholesterol levels were higher, the difference was statistically significant (P0.05). WC, diastolic blood pressure and MMSE score were significantly positive correlation, systolic blood pressure, heart rate, fasting blood glucose, There was a negative correlation between cholesterol and MMSE score (P0.05). MMSE score increased with the increase of age group showed a downward trend, the higher the age group, the higher the MMSE score lower than the normal value of the proportion of the larger. The scores of MMSE subitems in all subjects were significantly lower than the total scores of corresponding subitems (P0.01). Among them, memory (91.64%), attention and numeracy (74.84%), and orientation (70.27%) were the most common subitems. Memory (73.3%), reading ability (53%), writing (47%), and structural ability (47%) were the three items with the largest decrease. Conclusion Cognitive status of the elderly in rural areas is related to gender, age, years of education, smoking history, WC, and metabolic abnormalities such as body weight, fasting blood glucose and cholesterol are also closely related to the degree of cognitive impairment. The cognitive impairment of the elderly in rural areas is more extensive, including memory, attention and calculation ability, reading ability, writing ability and so on. Some subitems of MMSE scale should be adjusted in rural areas. The cognitive state of the elderly in rural areas is not optimistic, and the cognition state of the elderly in rural areas is not enough to understand Alzheimer's disease (AD), and the cognitive state of the elderly in rural areas needs to be paid more attention.
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R749.16
本文編號(hào)：2264082
[Abstract]:Objective to study the family history, personal history, height, weight, waist circumference, (WC), blood pressure, heart rate and fasting blood glucose in 1268 elderly people aged 60 years or over in Jixian rural area of Tianjin, and to study the family history, personal history, height, weight, waist circumference, blood pressure, heart rate and so on. The relationship between triglyceride (TG), cholesterol (TC) and cognitive dysfunction was studied. The characteristics of cognitive function of the elderly in rural areas of Tianjin were studied in order to provide evidence for improving the rate of awareness, diagnosis and treatment of cognitive dysfunction in rural areas. Methods basic information such as sex, age, education, history of hypertension and coronary heart disease, drinking and drinking tea were collected, height, weight, WC, blood pressure, heart rate, triglyceride were measured. Cholesterol, fasting blood glucose level, cognitive function were assessed with the simple Mental State Checklist (mini-mental state examination,MMSE). Cognitive impairment was assessed by MMSE scores of 17 in illiterate group, 22 in primary school group, and 26 in junior high school and above group. The subjects were divided into normal MMSE score group (700 patients with abnormal), MMSE score). Age, sex, years of education, height, body mass index, WC, blood pressure, heart rate, blood glucose, triglyceride, cholesterol were compared between the two groups. And differences in family history and drinking habits. The subjects were classified according to WC, body mass index, blood pressure, blood glucose, cholesterol and triglyceride values, and the effects of metabolic factors on cognitive status were investigated. The subjects were divided into different age groups to explore the effect of age on cognitive ability. The subitems of MMSE were analyzed to explore the extent and extent of cognitive impairment in rural population. Results the proportion of male, WC and diastolic blood pressure in MMSE normal group were higher than those in MMSE abnormal group, and the difference was statistically significant (P0.05). (P0.05), MMSE normal group was younger than that of MMSE abnormal group, higher education years and higher proportion of smoking history (P0.01). Systolic blood pressure was low, diastolic blood pressure was high, fasting blood glucose and cholesterol levels were higher, the difference was statistically significant (P0.05). WC, diastolic blood pressure and MMSE score were significantly positive correlation, systolic blood pressure, heart rate, fasting blood glucose, There was a negative correlation between cholesterol and MMSE score (P0.05). MMSE score increased with the increase of age group showed a downward trend, the higher the age group, the higher the MMSE score lower than the normal value of the proportion of the larger. The scores of MMSE subitems in all subjects were significantly lower than the total scores of corresponding subitems (P0.01). Among them, memory (91.64%), attention and numeracy (74.84%), and orientation (70.27%) were the most common subitems. Memory (73.3%), reading ability (53%), writing (47%), and structural ability (47%) were the three items with the largest decrease. Conclusion Cognitive status of the elderly in rural areas is related to gender, age, years of education, smoking history, WC, and metabolic abnormalities such as body weight, fasting blood glucose and cholesterol are also closely related to the degree of cognitive impairment. The cognitive impairment of the elderly in rural areas is more extensive, including memory, attention and calculation ability, reading ability, writing ability and so on. Some subitems of MMSE scale should be adjusted in rural areas. The cognitive state of the elderly in rural areas is not optimistic, and the cognition state of the elderly in rural areas is not enough to understand Alzheimer's disease (AD), and the cognitive state of the elderly in rural areas needs to be paid more attention.
【學(xué)位授予單位】：天津醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R749.16
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