【摘要】：目的:研究暴力犯罪嫌疑人和有攻擊行為的男性住院精神病患者血漿中5-羥色胺(5-hydroxy tryptamine,5-HT)的水平變化.方法:研究對(duì)象為男性暴力犯罪嫌疑人48例、具有攻擊行為的男性住院精神分裂癥患者37例、正常成年男性45例,年齡16~58歲.采用酶聯(lián)免疫吸附(ELISA)試劑盒定量測(cè)定血漿中5-HT水平,統(tǒng)計(jì)分析各組血漿5-HT水平的差異.結(jié)果:暴力犯罪嫌疑人和有攻擊行為的男性住院精神病患者血漿中5-HT水平均顯著低于正常人(P0.01),而暴力犯罪嫌疑人血漿5-HT水平又顯著低于有攻擊行為的男性住院精神病患者(P0.01).結(jié)論:暴力犯罪嫌疑人和有攻擊行為的男性精神病患者血漿中5-HT水平顯著降低,監(jiān)測(cè)有暴力傾向的罪犯和有攻擊行為的精神病患者血漿5-HT水平變化,可能有助于預(yù)防和減少暴力行為的發(fā)生.
[Abstract]:Aim: to study the changes of plasma serotonin (5-hydroxy tryptamine,5-HT) levels in violent suspects and male inpatients with aggressive behavior. Methods: the subjects were 48 male suspects of violence, 37 male inpatients with aggressive behavior and 45 normal adult males aged 16 to 58 years. The level of 5-HT in plasma was measured quantitatively by Elisa (ELISA) kit and the difference of plasma 5-HT level in each group was statistically analyzed. Results: the plasma 5-HT levels of the violent suspects and the male inpatients with aggressive behavior were significantly lower than those of the normal controls (P0.01), while the plasma 5-HT levels of the violent suspects were significantly lower than those of the male inpatients with aggressive behavior (P0.01). Conclusion: the levels of 5-HT in the plasma of violent criminal suspects and male psychotic patients with aggressive behavior were significantly decreased, and the changes of plasma 5-HT levels in violent criminals and aggressive mental patients were monitored. It may help to prevent and reduce violence.
【作者單位】： 佛山市第三人民醫(yī)院精神科;佛山市第三人民醫(yī)院檢驗(yàn)科;暨南大學(xué)醫(yī)學(xué)院生化教研室;
【基金】：佛山市科技發(fā)展專項(xiàng)資助項(xiàng)目(2012AA100161)
【分類號(hào)】：R749.3

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