發(fā)布時間：2018-06-08 00:04

  本文選題：難治性抑郁癥 + 治療　； 參考：《浙江大學(xué)》2012年碩士論文

【摘要】：抑郁癥是一種高患病率、高致殘率及高自殺率的嚴重精神疾患,造成顯著生活質(zhì)量下降、工作能力受損、健康狀況下降。在過去10年中,抗抑郁藥物研究取得了突飛猛進的進展。然而,在臨床上仍約有30%的抑郁癥患者對抗抑郁藥治療無反應(yīng)或反應(yīng)不完全,成為難治性抑郁癥(treatment-resi stant depression, TRD).由于難治性抑郁癥的發(fā)病率較高、病程遷延、治療緩解率低、治療時間長,且多共患其他疾病,因而成為臨床棘手的精神衛(wèi)生問題。對于一些臨床典型或特例的診療體會及時總結(jié),有利于診治的個體化,規(guī)范治療方案。本文報道浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院就診的三例難治性抑郁癥病人的診斷治療過程并綜述目前難治性抑郁癥的治療進展。
[Abstract]:Depression is a serious mental disorder with high prevalence, high disability rate and high suicide rate, which results in a significant decline in quality of life, impaired working ability and decreased health status. Research on antidepressants has made rapid progress over the past 10 years. However, about 30% of the patients with depression still have no or incomplete response to antidepressant drugs, so they become treatment-resi stant depressions. Because the incidence of refractory depression is high, the course of disease is prolonged, the rate of treatment and remission is low, the treatment time is long, and many other diseases are common, it has become a difficult problem of mental health in clinic. For some clinical typical or special cases, timely summary of diagnosis and treatment is beneficial to the individualization of diagnosis and treatment, standardized treatment plan. This paper reports the diagnosis and treatment of three patients with refractory depression in the first affiliated Hospital of Zhejiang University Medical College, and summarizes the current progress in the treatment of refractory depression.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R749.4

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本文編號：1993428