發(fā)布時(shí)間：2018-05-30 20:28

  本文選題：納洛酮治療 + 阿片類藥物成癮��； 參考：《中國(guó)全科醫(yī)學(xué)》2017年15期

【摘要】：背景愛爾蘭每年因阿片類藥物使用過(guò)量導(dǎo)致的死亡超過(guò)200例。納洛酮及阿片類藥物過(guò)量用藥的預(yù)防和管理應(yīng)成為醫(yī)療管理優(yōu)先考慮的內(nèi)容。納洛酮可有效治療阿片類藥物過(guò)量使用,目前正在考慮是否可以在無(wú)醫(yī)囑情況下更廣泛地使用納洛酮。目的明確和豐富全科醫(yī)生對(duì)阿片類藥物成癮、過(guò)量服用和納洛酮供應(yīng)的觀點(diǎn)和經(jīng)驗(yàn)。設(shè)計(jì)與場(chǎng)所對(duì)隸屬于愛爾蘭都柏林大學(xué)全科醫(yī)學(xué)系的全科醫(yī)生進(jìn)行匿名問卷調(diào)查。方法共有714例全科醫(yī)生受邀完成匿名問卷調(diào)查,將其結(jié)果與同期全科醫(yī)生實(shí)習(xí)生的調(diào)查結(jié)果進(jìn)行比較。結(jié)果 714例受試者中,共有448例(62.7%)做出回應(yīng)。1/3的全科醫(yī)生在城市、農(nóng)村和城鄉(xiāng)混合區(qū)。75%以上做出回應(yīng)的全科醫(yī)生的患者有不正當(dāng)使用阿片類藥物經(jīng)歷,25%的全科醫(yī)生開出美沙酮處方。1/3的全科醫(yī)生贊成在社區(qū)增加納洛酮的使用量;1/3的人愿意參加這樣一個(gè)計(jì)劃。與合格的全科醫(yī)生相比,采用納洛酮治療阿片類藥物過(guò)量使用、愿意參與納洛酮給藥的全科醫(yī)生實(shí)習(xí)生的比例更高。納洛酮鼻內(nèi)用藥優(yōu)于單次(P0.001)或多劑量的(P0.001)肌肉注射。66.1%(n=292)的全科醫(yī)生贊同更廣泛地使用納洛酮。結(jié)論全科醫(yī)生認(rèn)為有大量人群存在阿片類藥物使用障礙,但仍對(duì)其采用阿片類藥物激動(dòng)劑治療。全科醫(yī)生支持納洛酮的廣泛使用,并將參與其擴(kuò)展使用。因此迫切需要開展和評(píng)估支持基于全科醫(yī)生分配給藥的實(shí)施戰(zhàn)略。
[Abstract]:Background more than 200 deaths are caused by opioid overdose in Ireland each year. The prevention and management of naloxone and opioid overdose should be the priority of medical management. Naloxone is effective in the treatment of opioid overdose, and consideration is being given to the possibility of using naloxone more widely without medical advice. Objective to clarify and enrich the views and experiences of general practitioners on opioid addiction, overdose and naloxone supply. An anonymous questionnaire survey was conducted among general practitioners in the Department of General Medicine, University of Dublin, Ireland. Methods A total of 714 general practitioners were invited to complete anonymous questionnaires. Results A total of 448 out of 714 subjects responded to a third of the general practitioners in the city. More than .75% of responding general practitioners in rural and urban areas have had inappropriate use of opiates, 25% of general practitioners have prescribed methadone. 1 / 3 of general practitioners are in favour of increasing naloxone use in the community by 1 / 3. Ten percent of people are willing to take part in such a plan. Compared with qualified general practitioners, a higher proportion of interns were willing to take part in naloxone administration in the treatment of opioid overdose with naloxone. Naloxone intranasal medication is better than single dose of P0.001) or multiple dose of P0.001) intramuscular injection of .66.1 and naloxone 292) in favor of wider use of naloxone. Conclusion the general practitioners believe that a large number of people have opioid drug use disorders, but they still use opioid agonists. General practitioners support the widespread use of naloxone and will be involved in its expanded use. Therefore, there is an urgent need to develop and evaluate implementation strategies to support GP-based drug delivery.
【分類號(hào)】：R749.6

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