發(fā)布時(shí)間：2018-05-25 14:31

  本文選題：孤獨(dú)癥譜系障礙 + 高頻經(jīng)顱磁刺激　； 參考：《山東醫(yī)藥》2016年15期

【摘要】：目的比較不同部位經(jīng)顱重復(fù)高頻磁刺激聯(lián)合康復(fù)訓(xùn)練治療小兒孤獨(dú)癥譜系障礙的效果。方法 73例孤獨(dú)癥譜系障礙患兒隨機(jī)分為A組(24例)、B組(24例)、C組(25例),3組均采用傳統(tǒng)康復(fù)治療,A組在此基礎(chǔ)上加用經(jīng)顱重復(fù)高頻磁刺激左側(cè)Broca區(qū),B組在此基礎(chǔ)上加用經(jīng)顱重復(fù)高頻磁刺激左側(cè)背外側(cè)前額葉區(qū),比較各組孤獨(dú)癥行為量表(ABC量表,包含交往、感覺(jué)、軀體運(yùn)動(dòng)、語(yǔ)言、生活自理5個(gè)評(píng)分因子)評(píng)分、兒童孤獨(dú)癥評(píng)定量表(CARS量表)評(píng)分及0~6歲小兒神經(jīng)心理發(fā)育量表評(píng)分[以發(fā)育商(DQ)表示]。結(jié)果與治療前比較,A組治療后交往、語(yǔ)言、CARS量表評(píng)分降低,DQ值升高;與治療前比較,B組治療后軀體運(yùn)動(dòng)、生活自理、CARS量表評(píng)分降低,DQ值升高;與治療前比較,C組治療后交往、語(yǔ)言生活自理、CARS量表評(píng)分降低,DQ值升高;P均0.05。與C組比較,A組交往、語(yǔ)言、CARS量表評(píng)分降低,DQ值升高;與C組比較,B組軀體運(yùn)動(dòng)評(píng)分降低,DQ值升高;P均0.05。與B組比較,A組交往、語(yǔ)言、CARS量表評(píng)分降低,軀體運(yùn)動(dòng)評(píng)分及DQ值升高,P均0.05。結(jié)論經(jīng)顱重復(fù)高頻磁刺激額葉聯(lián)合康復(fù)訓(xùn)練可改善小兒孤獨(dú)癥譜系障礙癥狀,且刺激 Broca 區(qū)在交往和言語(yǔ)上的療效優(yōu)于刺激背外側(cè)前額葉區(qū)。復(fù)高頻磁刺激額葉聯(lián)合康復(fù)訓(xùn)練可改善小兒孤獨(dú)癥譜系障礙癥狀,且刺激Broca區(qū)在交往和言語(yǔ)上的療效優(yōu)于刺激背外側(cè)前額葉區(qū)。
[Abstract]:Objective to compare the effects of transcranial repetitive high frequency magnetic stimulation (THF) combined with rehabilitation training in the treatment of pediatric autism spectrum disorders. Methods 73 children with autism spectrum disorder were randomly divided into group A (n = 24), group B (n = 24), group C (n = 24) and group C (n = 25). All patients in group A were treated with traditional rehabilitation therapy. Transcranial repetitive high-frequency magnetic stimulation of left dorsolateral prefrontal lobe, The autistic behavior scale (ABC) was compared in each group, which included five score factors: communication, sensation, somatic movement, language and self-care of life. The rating scale for Autism in Children (cars) and the Neuropsychological Development scale for Children aged 0 to 6 (expressed by development quotient (DQ). Results compared with those before and after treatment, the scores of language cars scale decreased and DQ increased in group A, somatic movement and self-care car scale decreased after treatment in group B, and communication after treatment in group C was higher than that in group C before and after treatment. The score of cars scale decreased and DQ increased (P < 0.05). Compared with group C, the scores of language car scale decreased and DQ increased in group A, and the scores of somatic motor in group B decreased and DQ increased (P < 0.05), compared with group C, the scores of somatic motor scores in group B were significantly lower than those in group C (P < 0.05). Compared with group B, the scores of car scale decreased, the scores of somatic motor and DQ increased (P < 0.05). Conclusion Transcranial repetitive high frequency magnetic stimulation combined with rehabilitation training in frontal lobe can improve the symptoms of autism spectrum disorders in children, and stimulation of Broca area is more effective than stimulation of dorsolateral prefrontal lobe area in communication and speech. Combined rehabilitation training in frontal lobe with high frequency magnetic stimulation can improve the symptoms of autism spectrum disorders in children, and stimulation of Broca area is better than that of stimulation of dorsolateral prefrontal lobe area in communication and speech.
【作者單位】： 徐州市兒童醫(yī)院;
【基金】：徐州市科技項(xiàng)目(KC15SH051)
【分類號(hào)】：R749.94

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本文編號(hào)：1933505