本文選題：輕度認(rèn)知功能損害　切入點：促甲狀腺激素　出處：《中國老年學(xué)雜志》2017年08期

【摘要】：目的探討正常甲狀腺功能對老年人認(rèn)知功能的影響,明確甲狀腺功能是否為老年人輕度認(rèn)知功能損害(MCI)的危險因素。方法MCI患者和認(rèn)知功能正常人各80例,空腹抽血測血清促甲狀腺激素(TSH)、游離三碘甲狀腺原氨酸(FT3)、游離甲狀腺素(FT4)、血糖、血脂、血尿酸(UA),測量身高、體重和血壓。分析甲狀腺功能與認(rèn)知功能的相關(guān)性及老年人MCI的危險因素。結(jié)果 TSH與老年人MMSE評分負(fù)相關(guān)(B=-1.6,P=0.000),FT4則與其正相關(guān)(B=2.2,P=0.04),FT3與其無顯著相關(guān);正常高TSH組的MMSE評分明顯低于TSH中間組(P0.05);Logistic回歸分析發(fā)現(xiàn)TSH和FT4是老年人MCI的影響因素。結(jié)論老年人正常范圍內(nèi)甲狀腺功能輕度降低可以影響認(rèn)知功能。
[Abstract]:Objective to investigate the effect of normal thyroid function on cognitive function in the elderly and to determine whether thyroid function is a risk factor for mild cognitive impairment (MCI) in the elderly.Methods Serum thyrotropin (TSH), free triiodothyronine (FT3), free thyroxine (FT4), blood glucose, blood lipid and serum uric acid were measured in 80 patients with MCI and 80 patients with normal cognitive function. Height, weight and blood pressure were measured.To analyze the correlation between thyroid function and cognitive function and the risk factors of MCI in the elderly.緇撴灉 TSH涓庤，

本文編號：1705981