本文選題：抑郁發(fā)作亞臨床狀態(tài)　切入點：生物反饋　出處：《成都中醫(yī)藥大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：采用隨機單盲的設(shè)計方法,系統(tǒng)觀察抑郁發(fā)作亞臨床狀態(tài)生物反饋治療組和空白對照組患者3周之后的轉(zhuǎn)歸,探索生物反饋技術(shù)對抑郁發(fā)作亞臨床狀態(tài)的干預(yù)效果,以尋求一種可以影響抑郁發(fā)作亞臨床狀態(tài)向抑郁發(fā)作轉(zhuǎn)歸的治療方式,為抑郁發(fā)作亞臨床狀態(tài)的治療提供一種簡便有效且安全性高,副作用小的診療方式。 方法：將符合課題納入標(biāo)準(zhǔn)的抑郁發(fā)作亞臨床狀態(tài)患者隨機分為生物反饋治療組和空白對照組,生物反饋治療組采用腦電生物反饋治療儀干預(yù)3周,每周治療兩次,每周評定一次；空白對照組不采用任何方法干預(yù),觀察3周,每周評定一次。連續(xù)觀察3周后分析兩組患者的漢密爾頓抑郁量表(HAMD)、抑郁自評量表(SDS)、流調(diào)用抑郁自評量表(CES-D)和生活滿意度評分,并以HAMD的減分率作為總體療效標(biāo)準(zhǔn)評價生物反饋治療的療效。 結(jié)果：生物反饋治療組與空白對照組在對抑郁發(fā)作亞臨床狀態(tài)的干預(yù)方面有顯著差異,以]HAMD的減分率作為總體療效標(biāo)準(zhǔn),生物反饋治療組療效優(yōu)于空白對照組,差異具有統(tǒng)計學(xué)意義(P0.0001)。而在考慮病情程度的情況下,生物反饋治療組對HAMD評分在輕度和中度的均有效,且輕中度之間療效差異無統(tǒng)計學(xué)意義。SDS和CES-D的評分較治療前也明顯下降,生活滿意度評分升高,兩組間差異具有統(tǒng)計學(xué)意義(P0.0001)。 結(jié)論：生物反饋技術(shù)干預(yù)抑郁發(fā)作亞臨床狀態(tài),能降低受試者SDS、HAMD、 CES-D的評分,提高其生活滿意度。生物反饋技術(shù)能有效改善患者的抑郁發(fā)作亞臨床狀態(tài)的癥狀,降低抑郁發(fā)作亞臨床狀態(tài)向抑郁發(fā)作不良轉(zhuǎn)歸的趨勢。抑郁發(fā)作亞臨床狀態(tài)是能夠在一定程度上被控制或終止的,值得引起重視。生物反饋技術(shù)在抑郁發(fā)作亞臨床狀態(tài)的臨床診療方面效果肯定,值得深入研究。
[Abstract]:Objective: to investigate the effect of biofeedback on the subclinical state of depression after 3 weeks in patients in the subclinical state of depression treatment group and blank control group by using a randomized, single-blind design, and to explore the effect of biofeedback on the subclinical state of depression. In order to find a treatment that can affect the subclinical state of depression to depressive attack, and provide a simple, effective, safe and less side effect way for the treatment of depression subclinical state. Methods: patients with subclinical state of depression were randomly divided into biofeedback treatment group and blank control group. The biofeedback treatment group was treated with EEG biofeedback therapy for 3 weeks, twice a week. The blank control group did not take any intervention and observed for 3 weeks. Hamilton Depression scale (Hamd), self rating Depression scale (SDS), self rating Depression scale (SDS), flow call Depression scale (SDS) and Life satisfaction scale (life satisfaction) were analyzed after 3 weeks of continuous observation. The efficacy of biofeedback therapy was evaluated by using the score reduction rate of HAMD as the overall therapeutic standard. Results: there was significant difference between the biofeedback treatment group and the blank control group in the intervention of the subclinical state of depression. The efficacy of biofeedback treatment group was better than that of the blank control group. The difference was statistically significant (P 0.0001). However, the biofeedback treatment group was effective in mild and moderate HAMD scores, and the scores of CES-D and CES-D were significantly lower than those before treatment, and there was no significant difference between mild and moderate therapeutic effects. The score of life satisfaction increased, and the difference between the two groups was statistically significant (P 0.0001). Conclusion: biofeedback intervention can decrease the scores of SDSHAMDand CES-D and improve their life satisfaction. Biofeedback technique can effectively improve the symptoms of depression in patients with subclinical state. Reduce the tendency of depression subclinical state to depressive attack adverse outcome. Depression subclinical state can be controlled or terminated to some extent. The effect of biofeedback technique on the diagnosis and treatment of subclinical state of depression is positive and worthy of further study.
【學(xué)位授予單位】：成都中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R749.4

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