發(fā)布時間：2018-02-24 21:43

  本文關(guān)鍵詞： PD LOTCA 認(rèn)知障礙　出處：《昆明醫(yī)科大學(xué)》2012年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：應(yīng)用LOTCA量表初步探討帕金森病患者的認(rèn)知功能障礙及影響帕金森病患者認(rèn)知障礙的各相關(guān)因素。 方法：應(yīng)用洛文斯頓作業(yè)療法認(rèn)知評定中文量表(Loewenstein Occupational Therapy Cognitive Assessment Second Edition, LOTCA)(第二版)從定向力、感知覺、視運(yùn)動組織以及思維操作等方面評估研究對象的認(rèn)知情況。設(shè)置病例組和對照組的納入和排除標(biāo)準(zhǔn),選自2011年1月至10月份在昆明醫(yī)學(xué)院第一附屬醫(yī)院神經(jīng)內(nèi)科門診及住院部就診、新發(fā)并診斷為帕金森病的患者,共40例為病例組,以40例無帕金森病的患者、患者家屬或陪護(hù)人員等健康人群為對照組。按照年齡、教育程度、病程將研究對象分組評估,結(jié)果采用SPSS17.0統(tǒng)計(jì)軟件進(jìn)行統(tǒng)計(jì)學(xué)處理。 結(jié)果：1.兩樣本均數(shù)比較的t檢驗(yàn)顯示,對照組和病例組在視知覺、空間知覺、視運(yùn)動組織、思維操作、注意力與專注力5個子項(xiàng)目以及幾何圖形識別、臨摹幾何圖形、復(fù)繪二維圖形、插孔拼圖、彩色方塊拼圖、無色方塊拼圖、碎圖復(fù)原、畫鐘面、圖片排序、邏輯問題10個次級子項(xiàng)目方面的差異有統(tǒng)計(jì)學(xué)意義(P0.05)；2.兩樣本均數(shù)比較的t檢驗(yàn)及組間方差分析比較顯示,不同年齡組別、不同教育程度組別的對照組與病例組間以及不同病程的病例組間,均有一項(xiàng)或兩項(xiàng)以上的認(rèn)知功能方面的差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。3.在不同的年齡組中,對照組與病例組主要表現(xiàn)為思維操作、視運(yùn)動組織,注意力與專注力方面的差異具有統(tǒng)計(jì)學(xué)意義(P0.05)；不同教育程度組中,對照組與病例組主要表現(xiàn)為視知覺、視運(yùn)動組織、思維操作、注意力與專注力方面的差異具有統(tǒng)計(jì)學(xué)意義(P0.05)；不同病程中,患者的認(rèn)知功能障礙主要表現(xiàn)為動作運(yùn)用、視運(yùn)動組織方面(P0.05)。4.病例組中,不同教育程度組之間和不同病程組之間差異具有統(tǒng)計(jì)學(xué)差異.(P0.05),不同年齡組之間差異無明確統(tǒng)計(jì)學(xué)意義(P0.05)。對照組中,不同教育程度組之間差異具有統(tǒng)計(jì)學(xué)差異(P0.05),不同年齡組之間差異無明確統(tǒng)計(jì)學(xué)意義(P0.05)。5.對照組和病例組在視運(yùn)動組織與思維操作之間存在高度相關(guān)關(guān)系(r=0.773,P0.001),其余子項(xiàng)目間相關(guān)性均較低。 結(jié)論：1.帕金森病患者認(rèn)知功能障礙主要表現(xiàn)在視知覺、空間知覺、視運(yùn)動組織、思維操作、注意力與專注力方面。其中以視運(yùn)動組織、思維操作、注意力與專注力方面認(rèn)知受損為主。2.帕金森病患者的認(rèn)知功能障礙受到受教育程度、病程因素的影響,并且存在著一定規(guī)律：文化水平程度越低、病程越長認(rèn)知損害越明顯。反之,教育程度越高、病程越短認(rèn)知損害相對較輕。但是在本研究統(tǒng)計(jì)學(xué)結(jié)果中,年齡與患者認(rèn)知障礙之間沒有明顯關(guān)系。3.對照組和病例組中,視運(yùn)動組織與思維操作之間存在高度相關(guān)關(guān)系。
[Abstract]:Aim: to investigate the cognitive impairment of Parkinson's disease (PD) patients and the related factors affecting cognitive impairment by using LOTCA scale. Methods: using Loewenstein Occupational Therapy Cognitive Assessment Second Edition, Loewenstein Occupational Cognitive Assessment Second Edition, Loewenstein Therapy Cognitive Assessment Second Edition (second edition), from orientation, perception, perception, and perception, were used. The cognitive status of the subjects was evaluated in terms of exercise organization and mental manipulation, and the inclusion and exclusion criteria of the case group and the control group were set. From January 2011 to October, a total of 40 patients with Parkinson's disease were enrolled in the Department of Neurology, Department of Neurology, first affiliated Hospital of Kunming Medical College. According to the age, education level and course of disease, the subjects were divided into groups and evaluated. The results were analyzed by SPSS17.0 software. Results the t test of comparing the mean of the two samples showed that the control group and the case group had five sub-items of visual perception, spatial perception, visual movement organization, thinking operation, attention and concentration, as well as geometric pattern recognition. Double drawing 2D figure, Jack puzzle, color block puzzle, colorless block puzzle, fragment restoration, clock face, picture sort, The differences in the 10 sub-items of logical question were statistically significant (P 0.05) 2.The t test of the comparison of the mean numbers of the two samples and the analysis of variance among the two groups showed that different age groups, There was one or more cognitive function difference between the control group and the case group with different education level and the case group with different course of disease. There were significant differences in cognitive function among different age groups. The difference between the control group and the case group in the aspects of thinking operation, visual movement organization, attention and concentration was statistically significant (P 0.05), while in the different education level group, the control group and the case group mainly showed visual perception and visual movement tissue. The differences of thinking operation, attention and concentration were statistically significant (P 0.05). In different course of disease, the main manifestations of cognitive dysfunction in patients were movement use, visual movement organization (P 0.05). 4. In the case group, There was statistical difference between different education level groups and different course groups, but there was no significant difference between different age groups (P 0.05). In the control group, there was no significant difference between the two groups. There was statistical difference between different education level groups (P 0.05), but there was no significant difference between different age groups (P 0.05). There was a high correlation between visual motion organization and thinking operation in control group and case group. The correlation between eyes was low. Conclusion 1. Cognitive dysfunction in Parkinson's disease patients is mainly manifested in visual perception, spatial perception, visual motor organization, thinking operation, attention and concentration. Cognitive impairment in patients with Parkinson's disease is affected by educational level and course of disease, and there are certain rules: the lower the level of education, the lower the level of education. The longer the course of disease, the more obvious the cognitive impairment. On the contrary, the higher the education level, the shorter the course of cognitive impairment. However, there was no significant relationship between age and cognitive impairment in this study. 3. In the control group and the case group, there was no significant correlation between age and cognitive impairment. There is a high correlation between visual movement organization and thinking operation.
【學(xué)位授予單位】：昆明醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R749.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前8條

1 邵祥忠;景榮芳;秦延昆;;31例帕金森病患者認(rèn)知功能障礙臨床分析[J];臨床內(nèi)科雜志;2008年03期

2 徐翔,張霞萍,徐莉娟,包信一,魏文石;帕金森病、血管性癡呆、阿爾茨海默病患者的神經(jīng)心理學(xué)特點(diǎn)[J];中國臨床康復(fù);2004年13期

3 武冬冬;陳海波;李淑華;王新德;;中期帕金森病患者視覺空間工作記憶研究[J];診斷學(xué)理論與實(shí)踐;2007年01期

4 陳彤;王魯寧;王振福;;帕金森病癡呆[J];中風(fēng)與神經(jīng)疾病雜志;2007年05期

5 李玉梅,劉琨,王婷,朱友德;不同類型帕金森病患者的記憶障礙及相關(guān)因素[J];中國行為醫(yī)學(xué)科學(xué);2005年09期

6 燕鐵斌,馬超,郭友華,黃利榮;Loewenstein認(rèn)知評定量表(簡體中文版)的效度及信度研究[J];中華物理醫(yī)學(xué)與康復(fù)雜志;2004年02期

7 張善綱,范建中,陳平雁,張建宏,尹瑞雪;洛文斯頓作業(yè)療法認(rèn)知評定中文量表信度和內(nèi)在效度的初步研究[J];中華物理醫(yī)學(xué)與康復(fù)雜志;2004年09期

8 譚玉燕;陳生弟;;帕金森病癡呆的臨床特征及治療進(jìn)展[J];中華神經(jīng)科雜志;2006年06期

，

本文編號：1531818