本文關(guān)鍵詞： 美沙酮維持治療 靜脈吸毒 性功能 勃起功能障礙 維吾爾族男性　出處：《新疆醫(yī)科大學》2012年碩士論文　論文類型：學位論文

【摘要】：目的：了解烏魯木齊市海洛因成癮人群在接受美沙酮維持治療(Methadonemaintenance treatment，MMT)后的性功能狀況，探討美沙酮對吸毒人群性功能的潛在影響，，分析原因及提供對策。方法：采用“自制調(diào)查表”、“勃起功能障礙對生活質(zhì)量影響的調(diào)查表”和“國際勃起功能指數(shù)問卷調(diào)查表（IIEF-5）”，對烏魯木齊市7個MMT門診參加治療6個月以上的131名維吾爾族男性、烏魯木齊市強制戒毒所強制收留時間不超過一個月的進行戒毒的129名維吾爾族男性以及烏魯木齊市四個社區(qū)管轄內(nèi)130名從未吸毒的維吾爾族男性居民進行面對面訪談并填寫問卷。通過單因素分析和二分類Logistic回歸分析來探討各組男性性功能障礙的影響因素。結(jié)果:通過單因素分析結(jié)果顯示，三組人群在性欲、勃起維持時間、早泄、近三個月的性行為次數(shù)、性生活的滿意程度，勃起功能指數(shù)及勃起功能障礙對生活質(zhì)量的影響程度等方面差異均有統(tǒng)計學意義（P＜0.001）。多因素logistic回歸分析可知，分組不同的人群性功能狀況有一定的差異。與一般人群相比，MMT組和吸毒組人群的性功能狀況差異均有統(tǒng)計學意義（OR=17.340,5.590~53.782）,(OR=6.964，2.883~16.825)。而MMT組和吸毒組人群的性功能狀況相互比較，差異無統(tǒng)計學意義（OR=0.402, P=0.075）。影響性功能狀況的因素有：年齡和前列腺炎。與20～29歲組男性相比，30～39歲組和≥40歲組男性性功能狀況差異均有統(tǒng)計學意義（OR=2.506,1.218~5.158），（OR=2.763,1.016~7.519）。患有前列腺炎的男性發(fā)生性功能障礙的危險性是未患前列腺炎者的2.257倍（OR=2.257,1.021~4.993）。結(jié)論：吸毒會導致男性性功能障礙。美沙酮維持治療不是導致男性海洛因成癮者性功能障礙的主要原因，但大劑量的藥物維持治療會加重對性功能的影響。低維持劑量則會改善性功能狀況。因此調(diào)整好維持劑量將能有效地改善該人群的性功能狀況。
[Abstract]:Objective: to investigate the sexual function of heroin addicts in Urumqi after receiving methadone maintenance therapy (MMTT), and to explore the potential effect of methadone on sexual function of drug addicts. Methods: Self-made questionnaire, questionnaire on the influence of erectile dysfunction on quality of life and International erectile Index questionnaire (IIEF-5) were used to treat 7 MMT outpatients in Urumqi. 131 Uighur men treated for more than six months, In Urumqi, 129 Uygur men who had been detoxified for no more than a month and 130 Uighur male residents who had never used drugs in four communities under the jurisdiction of Urumqi City were held face to face in a forced drug treatment center for no more than one month. To investigate the influencing factors of male sexual dysfunction in each group by univariate analysis and two-classification Logistic regression analysis. Results: univariate analysis showed that, Three groups of people in the sexual desire, erectile maintenance time, premature ejaculation, the last three months of sexual activity, sexual satisfaction, There were significant differences in erectile function index and the degree of influence of erectile dysfunction on quality of life (P < 0.001). Multivariate logistic regression analysis showed that there were significant differences in the index of erectile function and the degree of influence of erectile dysfunction on quality of life. There were some differences in sexual function status among different groups of people. There were significant differences in sexual function status between MMT group and drug addicts group compared with the general population. There were significant differences in sexual function status between MMT group and drug addicts group, and the sexual function status of MMT group and drug addicts group were compared with each other. There was no significant difference in sexual function status between male and female. The factors influencing sexual function were age and prostatitis. There were significant differences in sexual function between 30 and 39 years old men and more than 40 years old men compared with 20 and 29 years old men. There was significant difference in the sexual function status of OR2.5061.21885.1580.There were significant differences in the sexual function status of the men with prostatitis (OR 2.763P 1.0167.519). The risk of sexual dysfunction in men was 2.257 times as high as that in patients without prostatitis. Conclusion: drug use may lead to sexual dysfunction in men. Methadone maintenance therapy is not the main cause of sexual dysfunction in heroin addicts. However, large dose of drug maintenance therapy will aggravate the influence on sexual function. Low maintenance dose will improve sexual function. Therefore, adjusting maintenance dose can effectively improve the sexual function of the population.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R749.64

【參考文獻】

相關(guān)期刊論文 前10條

1 劉建波;地力夏提·亞合甫;李凡;;美沙酮維持治療及其有效性[J];地方病通報;2007年01期

2 彭亦如,張紹雨,林昌銓;毒品分析研究進展[J];福建公安高等�？茖W校學報;2003年02期

3 姚建龍;我國現(xiàn)行戒毒體系的反思與重構(gòu)[J];青少年犯罪問題;2002年03期

4 楊放;林鵬;龍其穗;何群;李艷;劉勇鷹;王曄;付笑冰;;阿片類物質(zhì)成癮者參加社區(qū)美沙酮維持治療影響因素的定性研究[J];華南預(yù)防醫(yī)學;2008年03期

5 于新蕊;維持療法在嗎啡類成癮性治療中的地位[J];國外醫(yī)學(社會醫(yī)學分冊);2000年01期

6 韓麗軍;;吸毒者的胸部病變影像學特點分析[J];海南醫(yī)學;2006年02期

7 吳尊友;大力開展我國艾滋病行為干預(yù)研究[J];疾病控制雜志;2000年01期

8 龔俊平,龐琳,吳尊友;美沙酮維持治療病人保持情況及其影響因素[J];疾病控制雜志;2005年03期

9 李杏莉;歐秋英;譚紅專;孫振球;張恒;陳夢施;;長沙市美沙酮門診的吸毒者調(diào)查[J];疾病控制雜志;2008年01期

10 錢若兵,傅先明,汪業(yè)漢;毒品成癮的神經(jīng)機制、治療現(xiàn)狀和進展[J];立體定向和功能性神經(jīng)外科雜志;2005年03期

本文編號：1498770