重癥腦卒中患者高敏C反應(yīng)蛋白的動態(tài)變化及其與入院急性生理學(xué)和慢性健康狀況評分的關(guān)系
發(fā)布時間:2019-06-09 12:22
【摘要】:目的觀察入院重癥腦卒中患者血清高敏C反應(yīng)蛋白(hsCRP)的動態(tài)變化,探討hsCRP與急性生理學(xué)和慢性健康狀況評分(APACHEⅡ評分)的相關(guān)性。方法入選2013年1月1日至2015年12月31日于重癥監(jiān)護室(ICU)住院治療的急性腦卒中患者237例,根據(jù)預(yù)后情況分為存活組(n=187)和死亡組(n=50),監(jiān)測和比較兩組患者入住ICU后1、3、5和7d的hsCRP及血壓的變化情況,分析hsCRP和入院時的APACHEⅡ評分的相關(guān)性。結(jié)果入選的重癥腦卒中患者入院時即查的血清hsCRP水平均高于正常參考值上限。存活組患者血壓和hsCRP水平隨著病情好轉(zhuǎn)逐步下降,而死亡組患者h(yuǎn)sCRP的水平呈上升趨勢(P趨勢0.05)。死亡組患者入院時的APACHEⅡ評分顯著高于存活組(31.58±6.96比15.24±4.63,P0.01)。Pearson線性相關(guān)分析顯示,重癥腦卒中患者h(yuǎn)sCRP水平與入院APACHEⅡ評分呈正相關(guān)(r=0.416,P0.01);非條件Logistic回歸分析顯示,hsCRP是入院重癥腦卒中患者APACHEⅡ評分的影響因素(OR3.03,95%CI 1.82~9.27,P0.01)。結(jié)論入院重癥腦卒中存活組患者的血壓和hsCRP水平逐步下降,而死亡組患者h(yuǎn)sCRP的水平呈上升趨勢,且hsCRP水平與入院APACHEⅡ評分呈正相關(guān)。
[Abstract]:Objective to observe the dynamic changes of serum Gao Min C-reactive protein (hsCRP) in patients with severe stroke, and to explore the correlation between hsCRP and acute physiology and chronic health status score (APACHE II score). Methods from January 1, 2013 to December 31, 2015, 237 patients with acute stroke hospitalized in intensive care unit (ICU) were divided into survival group (n 鈮,
本文編號:2495552
[Abstract]:Objective to observe the dynamic changes of serum Gao Min C-reactive protein (hsCRP) in patients with severe stroke, and to explore the correlation between hsCRP and acute physiology and chronic health status score (APACHE II score). Methods from January 1, 2013 to December 31, 2015, 237 patients with acute stroke hospitalized in intensive care unit (ICU) were divided into survival group (n 鈮,
本文編號:2495552
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