血糖水平對重組組織型纖維蛋白酶原激活劑靜脈溶栓治療急性缺血性腦卒中預(yù)后的影響
發(fā)布時間:2019-05-09 23:06
【摘要】:目的探討血糖水平對重組組織型纖維蛋白酶原激活劑(rt-PA)靜脈溶栓治療急性缺血性腦卒中預(yù)后的影響。方法選擇2014年5月至2015年7月在該院接受靜脈rt-PA溶栓治療的118例急性缺血性腦卒中患者。根據(jù)溶栓前血糖水平分為血糖正常組(血糖7.8 mmol/L,n=49),血糖偏高組(7.8~11.1 mmol/L,n=42),高血糖組(血糖11.1 mmol/L,n=27)。采用Rankin量表(mRS)評價(jià)神經(jīng)功能恢復(fù)情況,根據(jù)mRS評分分為預(yù)后良好組(n=71)和預(yù)后不良組(n=47)。分析影響rt-PA靜脈溶栓治療急性缺血性腦卒中預(yù)后的因素,比較不同血糖水平患者的預(yù)后。結(jié)果(1)多因素Logistic回歸分析顯示,影響rt-PA預(yù)后的危險(xiǎn)因素有:溶栓前血糖、溶栓前美國國立衛(wèi)生研究院卒中量表(NIHSS)評分、伴有糖尿病、溶栓后2 h及24 h收縮壓。(2)血糖偏高組和高血糖組顱內(nèi)出血發(fā)生率、癥狀性顱內(nèi)出血發(fā)生率、病死率、預(yù)后不良發(fā)生率明顯高于血糖正常組(P0.05)。結(jié)論溶栓前血糖≥7.8 mmol/L的急性缺血性腦卒中患者rt-PA靜脈溶栓治療預(yù)后較差,血糖水平是影響靜脈rt-PA溶栓治療預(yù)后的獨(dú)立因素。
[Abstract]:Objective to investigate the effect of blood glucose level on the prognosis of acute ischemic stroke treated with recombinant tissue protease activating agent (rt-PA). Methods from May 2014 to July 2015, 118 patients with acute ischemic stroke were treated with intravenous rt-PA thrombolysis. According to the level of blood glucose before thrombolysis, they were divided into normal blood glucose group (7.8 mmol/L,n=49), hyperglycemia group (7.8 鈮,
本文編號:2473159
[Abstract]:Objective to investigate the effect of blood glucose level on the prognosis of acute ischemic stroke treated with recombinant tissue protease activating agent (rt-PA). Methods from May 2014 to July 2015, 118 patients with acute ischemic stroke were treated with intravenous rt-PA thrombolysis. According to the level of blood glucose before thrombolysis, they were divided into normal blood glucose group (7.8 mmol/L,n=49), hyperglycemia group (7.8 鈮,
本文編號:2473159
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