【摘要】：目的了解老年非瓣膜性房顫伴急性腦梗死患者的血漿尿酸、腦鈉肽(BNP)水平的變化意義及與CHADS2的關(guān)系。方法對(duì)入住該院的188例老年非瓣膜性房顫患者分為急性腦梗死及非急性腦梗死組,測(cè)定BNP、尿酸水平,并了解其在CHADS2評(píng)分中的變化。結(jié)果急性腦梗死組的BNP及尿酸水平較非急性腦梗死組明顯增高(均P=0.000)。隨著CHADS2評(píng)分的增高,BNP水平逐漸升高(P=0.036),但尿酸無類似趨勢(shì)。結(jié)論 BNP、尿酸增高可能是老年非瓣膜病心房顫動(dòng)患者發(fā)生腦梗死的危險(xiǎn)因素,且隨著CHADS2分值升高,BNP水平也越高。
[Abstract]:Aim to investigate the changes of plasma uric acid and brain natriuretic peptide (BNP) levels in elderly patients with nonvalvular atrial fibrillation with acute cerebral infarction (ACI) and its relationship with CHADS2. Methods 188 elderly patients with non-valvular atrial fibrillation were divided into two groups: acute cerebral infarction group and non-acute cerebral infarction group. The level of BNP, uric acid was measured and the changes in CHADS2 score were observed. Results the levels of BNP and uric acid in the acute cerebral infarction group were significantly higher than those in the non-acute cerebral infarction group (P < 0. 000). With the increase of CHADS2 score, the level of BNP increased gradually (P < 0. 036), but there was no similar tendency of uric acid. Conclusion the increase of BNP, uric acid may be a risk factor for cerebral infarction in elderly patients with non-valvular atrial fibrillation, and the higher the level of BNP is with the increase of CHADS2 score.
【作者單位】： 海南省人民醫(yī)院醫(yī)療保健三區(qū);
【基金】：海南省衛(wèi)計(jì)委資金資助項(xiàng)目(No.13A200003)
【分類號(hào)】：R541.75;R743.3

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