【摘要】：目的探討參麥注射液對老年急性膿毒血癥患者血清C反應(yīng)蛋白(CRP)、降鈣素原(PCT)、腫瘤壞死因子(TNF)-α水平的影響。方法選取老年急性膿毒血癥患者96例,隨機(jī)分為兩組,各48例。對照組采用常規(guī)治療,觀察組在對照組基礎(chǔ)上采用參麥注射液治療,采用雙抗體夾心酶聯(lián)免疫吸附(DAS-ELISA)檢測血清CRP、PCT、TNF-α水平,參照序貫器官衰竭評分(SOFA)與急性生理學(xué)與慢性健康狀況評分(APACHE)Ⅱ標(biāo)準(zhǔn)評定預(yù)后狀況。結(jié)果觀察組治療有效率明顯高于對照組(P0.05)。治療后,兩組血清指標(biāo)(CRP、PCT、TNF-α)與預(yù)后狀況(SOFA、APACHEⅡ)均明顯低于治療前,觀察組上述指標(biāo)均明顯低于對照組(P0.05),兩組患者均未出現(xiàn)任何藥物不良反應(yīng)。結(jié)論參麥注射液有助于顯著降低老年急性膿毒血癥患者血清CRP、PCT、TNF-α等炎癥介質(zhì)水平,改善臨床療效與預(yù)后。
[Abstract]:Objective to investigate the effect of Shenmai injection on serum C-reactive protein (CRP),) calcitonin procalcitonin (PCT),) tumor necrosis factor (TNF)-偽) levels in elderly patients with acute sepsis. Methods 96 aged patients with acute sepsis were randomly divided into two groups, 48 cases each. The control group was treated with routine therapy, the observation group was treated with Shenmai injection on the basis of the control group, and the serum CRP,PCT,TNF- 偽 level was detected by double antibody sandwich enzyme linked immunosorbent assay (DAS-ELISA). Prognostic status was evaluated by (SOFA) and (APACHE) 鈪，

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