發(fā)布時間：2018-07-16 19:48

【摘要】：目的:通過分析紅細胞分布寬度(RDW)變化規(guī)律評估其對ICU院內(nèi)感染重癥病患者遠期預(yù)后的影響。方法:2014年1月至2015年6月收集重癥醫(yī)學科院內(nèi)感染患者數(shù)據(jù),以RDW指標分為正常組(15%)和增高組(15%),對比兩組院內(nèi)感染患者基礎(chǔ)狀況,生化指標,APACHEII評分,查爾森合并癥指數(shù)等是否存在差異性,評估兩組患者28、90 d生存率及死亡風險。結(jié)果:共有66例患者入選,RDW增高組(31例)與RDW正常組(35例)相比28、90 d死亡風險明顯增高(P0.05),COX多因素風險結(jié)果顯示RDW(OR=1.110,95%CI=1.011~1.219,P=0.029)為獨立的風險因素。結(jié)論:ICU重癥患者發(fā)生醫(yī)院感染且伴有RDW增高時提示遠期死亡風險增加。
[Abstract]:Objective: to evaluate the effect of RDW on the long term prognosis of patients with severe nosocomial infection in ICU. Methods: from January 2014 to June 2015, the data of nosocomial infection patients in intensive care department were collected and divided into normal group (15%) and elevated group (15%) according to the RDW index. The basic status, biochemical index and Apache II score of nosocomial infection patients were compared between the two groups. Whether there was any difference in Charlson's complication index was used to evaluate the 2890 day survival rate and the risk of death in the two groups. Results: a total of 66 patients were enrolled in the RDW increased group (31 cases) and the RDW normal group (35 cases). The risk of death on day 2890 was significantly higher than that in the RDW group (P0.05). The multivariate risk of Cox showed that RDW (OR1.11010 ~ 95CII 1.0111.219P0.029) was an independent risk factor. Conclusion nosocomial infection with increased RDW in severe ICU patients suggests an increased risk of long-term death.
【作者單位】： 暨南大學附屬珠海醫(yī)院廣東省珠海市人民醫(yī)院重癥醫(yī)學科;
【基金】：珠海市科技計劃項目(編號:2013D0401990020)
【分類號】：R459.7;R197.32
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本文編號：2127488