重癥監(jiān)護(hù)室危重膿毒癥病原菌分布及其預(yù)后分析
發(fā)布時(shí)間:2018-07-01 11:28
本文選題:嚴(yán)重膿毒癥 + 膿毒性休克; 參考:《廣東醫(yī)學(xué)》2016年S1期
【摘要】:目的探討重癥監(jiān)護(hù)室(ICU)危重膿毒癥的病原菌特點(diǎn)及影響患者預(yù)后的危險(xiǎn)因素,提高ICU危重膿毒癥的總體救治水平。方法回顧性分析嚴(yán)重膿毒癥、膿毒癥休克患者1 088例的臨床資料,如基本資料、致病菌分布及生化指標(biāo)等,按患者出院時(shí)的預(yù)后分為院內(nèi)死亡組與康復(fù)出院組,通過非條件logistic回歸模型對相關(guān)因素進(jìn)行多因素分析。結(jié)果康復(fù)出院580例(53.3%)。院內(nèi)死亡組平均年齡、APACHE-Ⅱ評(píng)分、降鈣素原、血乳酸水平、革蘭陰性菌感染比例及耐藥鮑曼不動(dòng)桿菌感染比例均高于康復(fù)出院組,但院內(nèi)死亡組血小板計(jì)數(shù)、血清白蛋白低于康復(fù)出院組。多因素logistic回歸分析顯示年齡、APACHE-Ⅱ評(píng)分、血乳酸、降鈣素原及血清白蛋白是預(yù)后的獨(dú)立影響因素。結(jié)論 ICU危重膿毒癥在臨床上有較高的發(fā)病率和病死率。年齡、APACHE-Ⅱ評(píng)分、血乳酸、降鈣素原及血清白蛋白是患者預(yù)后的影響因素。
[Abstract]:Objective to investigate the pathogenic bacteria characteristics of critical sepsis in intensive care unit (ICU) and the risk factors affecting the prognosis of the patients, and to improve the overall treatment level of critical sepsis in ICU. Methods the clinical data of 1088 patients with severe sepsis and septic shock were analyzed retrospectively, such as basic data, distribution of pathogenic bacteria and biochemical indexes. The patients were divided into hospital death group and rehabilitated discharge group according to their prognosis. The related factors were analyzed by non-conditional logistic regression model. Results 580 cases (53.3%) recovered and discharged from hospital. APACHE- 鈪,
本文編號(hào):2087637
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