Padua量表及改良后Padua量表在創(chuàng)傷外科患者VTE風(fēng)險(xiǎn)評(píng)估中的應(yīng)用效果
發(fā)布時(shí)間:2018-06-22 18:49
本文選題:靜脈血栓栓塞癥 + 靜脈血栓栓塞癥風(fēng)險(xiǎn)評(píng)估表; 參考:《青島大學(xué)》2017年碩士論文
【摘要】:目的:通過(guò)回顧性采集患者病歷資料評(píng)價(jià)Padua量表及改良后Padua量表在創(chuàng)傷外科患者靜脈血栓栓塞癥風(fēng)險(xiǎn)評(píng)估中的效果。方法:回顧性收集青島大學(xué)附屬醫(yī)院自2015年11月至2016年9月收入創(chuàng)傷外科住院的590例患者的住院資料,其中25例確診為VTE患者。分別應(yīng)用Caprini量表、Padua量表及改良后Padua量表、RAP評(píng)分對(duì)590例患者進(jìn)行評(píng)分。通過(guò)分析評(píng)分結(jié)果:評(píng)價(jià)各量表評(píng)估為高危患者中確診為靜脈血栓栓塞癥的患者所占比例,進(jìn)行率的比較;構(gòu)建受試者工作特征曲線(xiàn)(ROC)模型,比較改良后Padua量表與Caprini量表、Padua量表、RAP評(píng)分的靈敏度、特異度和約登指數(shù)。結(jié)果:回顧性采集590例創(chuàng)傷外科住院患者資料。Caprini量表評(píng)價(jià)為高;颊咧嘘(yáng)性率占6.93%、Padua量表評(píng)價(jià)為高;颊咧嘘(yáng)性率占8.75%、改良后Padua量表陽(yáng)性率占8.42%,各量表相比差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);由構(gòu)建ROC曲線(xiàn)模型所得:Caprini量表、Padua量表、改良后Padua量表、RAP評(píng)分評(píng)價(jià)創(chuàng)傷外科患者靜脈血栓栓塞癥風(fēng)險(xiǎn)的曲線(xiàn)下面積(AUC)分別為0.808(95%CI=0.754~0.862)、0.751(95%CI=0.676~0.826)、0.773(0.700~0.847)和0.774(95%CI=0.687~0.0.860),最佳切點(diǎn)的(Caprini量表≥3.5分、Padua量表≥3.5分、改良后Padua量表≥4.5分、RAP評(píng)分≥6.5分)的靈敏度分別為100%、96%、96%和80%,特異度分別為55.4%、55.8%、56.1%和71.5%,約登指數(shù)分別為0.554、0.518、0.521和0.515;Caprini量表、Padua量表、改良后Padua量表、RAP評(píng)分對(duì)創(chuàng)傷外科患者靜脈血栓栓塞癥的風(fēng)險(xiǎn)評(píng)估均有統(tǒng)計(jì)學(xué)意義(均P0.05)。結(jié)論:Padua量表及改良后Padua量表適用于對(duì)創(chuàng)傷外科患者靜脈血栓栓塞癥風(fēng)險(xiǎn)評(píng)估。
[Abstract]:Objective: to evaluate the efficacy of Padua scale and modified Padua scale in evaluating the risk of venous thromboembolism in trauma surgery patients. Methods: the data of 590 patients admitted to trauma surgery from November 2015 to September 2016 in Qingdao University affiliated Hospital were collected retrospectively. 25 of them were diagnosed as VTE patients. Caprini scale Padua scale and modified Padua scale were used to evaluate 590 patients. Through the analysis of scoring results: to evaluate the proportion and rate of patients diagnosed with venous thromboembolism (VTE) in the high risk patients assessed by various scales, to construct the model of operating characteristic curve (ROC) of subjects, and to compare the percentage of patients with venous thromboembolism (VTE). The sensitivity, specificity and Jorden index of modified Padua scale and Caprini scale / Padua scale were compared. Results: a retrospective study of 590 inpatients with trauma surgery. Caprini scale showed that the positive rate of high risk patients was 6.93% and the positive rate of Padua scale was 8.75%, and the positive rate of modified Padua scale was 8.42%. There was no statistical significance (P0.05). The area under curve (AUC) of modified Padua scale / rap score for evaluating the risk of venous thromboembolism in trauma surgery patients was 0.808 (95CI0.754 / 0.862) and 0.751 (95CI0.760.826), 0.773 (0.70070.847) and 0.774 (95CI0.6870.0.860), respectively. The sensitivity of the improved Padua scale 鈮,
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