重癥感染降階梯治療失敗的相關(guān)性研究
發(fā)布時間:2018-06-22 05:37
本文選題:重癥感染 + 階梯治療 ; 參考:《中國醫(yī)院藥學雜志》2016年04期
【摘要】:目的:對重癥感染患者降階梯治療失敗的危險因素進行研究,為合理進行降階梯治療提供科學依據(jù)。方法:以某院2007年1月-2014年12月412例采用降階梯治療重癥感染患者為調(diào)查對象,由醫(yī)院信息管理系統(tǒng)導出所需的各項調(diào)查項目,再采用Excel統(tǒng)一填寫各項調(diào)查項目,對412例調(diào)查項目齊全的病例進行研究,數(shù)據(jù)采用SPSS 13.0統(tǒng)計軟件進行分析,各變量現(xiàn)經(jīng)單因素分析后,選擇具有統(tǒng)計學差異的因素再進行非條件Logistic回歸分析。結(jié)果:高齡(≥70歲)、多重耐藥菌感染、低蛋白血癥(30 g)、呼吸機輔助呼吸時間過長(≥7 d)為降階梯治療失敗的危險因素,其中高齡(≥70歲)、多重耐藥菌感染、低蛋白血癥(30 g)為降階梯治療失敗的獨立危險因素。結(jié)論:重癥感染的患者如存在高齡(≥70歲)、多重耐藥菌感染、低蛋白血癥(30 g)因素,則盡量不要采用降階梯治療。如果同時存在高齡(≥70歲)和多重耐藥菌感染或高齡(≥70歲)和低蛋白血癥(30 g)的重癥感染患者不能采用降階梯治療法。
[Abstract]:Objective: to study the risk factors of the failure of descending ladder therapy in patients with severe infection. Methods: 412 patients with severe infection were investigated from January 2007 to December 2014. The items of investigation were derived from the hospital information management system, and the investigation items were filled out by Excel. 412 cases with complete investigation items were studied. The data were analyzed by SPSS 13.0 statistical software. After single factor analysis, the factors with statistical difference were selected for non-conditional logistic regression analysis. Results: old age (鈮,
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