本文選題：急性腦梗死 + 脂蛋白相關(guān)磷脂酶A��； 參考：《中國動(dòng)脈硬化雜志》2017年09期

【摘要】：目的探討急性腦梗死患者脂蛋白相關(guān)磷脂酶A2(Lp-PLA2)水平的變化特點(diǎn)及其與頸動(dòng)脈粥樣硬化斑塊的關(guān)系。方法選取2013年6月至2014年10月來我院就診確診的82例急性腦梗死患者作為腦梗死組,并選取同期我院體檢者82例作為對照組,彩色多普勒超聲檢測頸總動(dòng)脈粥樣硬化斑塊,ELISA檢測血清Lp-PLA2水平,Spearman相關(guān)分析急性腦梗死患者血清Lp-PLA2水平變化特點(diǎn)及其與梗死面積、頸動(dòng)脈粥樣硬化斑塊Crouse積分之間的關(guān)系。結(jié)果腦梗死組Lp-PLA2、hs-CRP、TG、TC及LDLC的水平顯著高于對照組,HDLC水平顯著低于對照組(P0.05);頸動(dòng)脈粥樣硬化斑塊Ⅰ級、Ⅱ級和Ⅲ級三組間Crouse積分、Lp-PLA2水平比較具有顯著性差異,且隨分級增加Lp-PLA2水平升高(P0.05);急性腦梗死患者Lp-PLA2水平隨神經(jīng)功能損傷程度增加而升高,Lp-PLA2水平與Crouse積分、梗死面積呈正相關(guān)(r=0.823和r=0.879,P0.05)。結(jié)論 Lp-PLA2水平與動(dòng)脈粥樣硬化性腦梗死有關(guān),可反映患者頸動(dòng)脈粥樣硬化斑塊及腦梗死面積情況,可作為腦梗死預(yù)測指標(biāo)。
[Abstract]:Objective to investigate the changes of lipoprotein associated phospholipase A _ 2 (Lp-PLA _ 2) in patients with acute cerebral infarction and its relationship with carotid atherosclerotic plaque. Methods from June 2013 to October 2014, 82 patients with acute cerebral infarction were selected as cerebral infarction group, and 82 patients in our hospital were selected as control group. Detection of Common carotid Atherosclerotic plaque by Color Doppler Ultrasound Elisa Detection of Serum Lp-PLA2 level Spearman correlation Analysis of changes in Serum Lp-PLA2 levels and the relationship between Lp-PLA2 levels and infarct size and carotid Atherosclerotic plaque Crouse score in patients with Acute Cerebral Infarction (ACI). Results the levels of TGG TC and LDLC in cerebral infarction group were significantly higher than those in control group (P 0.05), and the levels of Crouse integral Lp-PLA2 in carotid atherosclerotic plaque grade 鈪，

本文編號：2026206