吸煙對(duì)不同性別、年齡人群急性ST段抬高型心肌梗死發(fā)病風(fēng)險(xiǎn)的相關(guān)性研究
發(fā)布時(shí)間:2018-05-09 02:11
本文選題:心肌梗死 + 吸煙。 參考:《中國(guó)循環(huán)雜志》2016年09期
【摘要】:目的:探討吸煙對(duì)不同性別、年齡人群急性ST段抬高型心肌梗死(STEMI)的致病風(fēng)險(xiǎn)是否存在差異。方法:采用病例對(duì)照研究設(shè)計(jì)(1:1匹配),入選我院2010-01-14至2016-01-27連續(xù)收治的2 026例明確診斷為STEMI的患者和2 026例按性別、年齡(±2歲)匹配的同期入院行健康體檢或擇期外科手術(shù)的對(duì)照人群,進(jìn)行吸煙與STEMI發(fā)病風(fēng)險(xiǎn)的相關(guān)性分析。結(jié)果:吸煙是男性STEMI的重要危險(xiǎn)因素,且與年齡呈負(fù)相關(guān):吸煙患STEMI的青年男性(≤45歲)調(diào)整比值比(OR)=7.000[95%可信區(qū)間(CI):4.235~11.570],中年男性(46~59歲)調(diào)整OR=5.296(95%CI:3.904~7.185),老年男性(≥60歲)調(diào)整OR=4.686(95%CI:2.860~4.751)。結(jié)論:吸煙是STEMI的主要危險(xiǎn)因素,但其相對(duì)致病風(fēng)險(xiǎn)度存在年齡和性別差異,對(duì)青年男性的相對(duì)致病風(fēng)險(xiǎn)最高且是最主要的致病因素。
[Abstract]:Objective: to investigate whether smoking affects the risk of STEMIs in patients with acute ST-segment elevation myocardial infarction (STEMI) in different sex and age groups. Methods: a case-control study was carried out to select 2 026 patients with STEMI and 20 026 patients by sex who were admitted to our hospital from 2010-01-14 to 2016-01-27. The correlation between smoking and risk of STEMI was analyzed in matched control population with age (鹵2 years) who were hospitalized for physical examination or elective surgery at the same time. Results: smoking was an important risk factor for male STEMI, and it was negatively correlated with age: the adjusted ratio of young men (鈮,
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