本文選題：休克 + 膿毒性��； 參考：《中國全科醫(yī)學(xué)》2017年34期

【摘要】：目的探討參麥注射液聯(lián)合血液灌流對膿毒性休克患者血流動力學(xué)及組織灌注的影響。方法選取2015年1月—2016年8月紹興市人民醫(yī)院重癥醫(yī)學(xué)科收治的膿毒性休克患者60例,采用隨機(jī)數(shù)字表法分為A、B、C 3組,每組20例。A組患者采用膿毒癥常規(guī)治療法治療,B組患者在A組治療的基礎(chǔ)上加用參麥注射液治療,C組患者在B組治療的基礎(chǔ)上采用血液灌流治療。比較3組患者治療前及治療7 d后的血流動力學(xué)指標(biāo)[包括心臟指數(shù)(CI)、外周血管阻力指數(shù)(SVRI)、血管外肺水指數(shù)(EVLWI)]、急性生理功能和慢性健康狀況評分系統(tǒng)Ⅱ(APACHEⅡ)評分及實(shí)驗室檢測指標(biāo)[包括血乳酸(Lac)、前降鈣素(PCT)、C反應(yīng)蛋白(CRP)、腦鈉肽(BNP)]。結(jié)果治療前3組患者CI、SVRI、EVLWI、APACHEⅡ評分比較,差異無統(tǒng)計學(xué)意義(P0.05)。治療后B、C組患者CI、SVRI高于A組,EVLWI、APACHEⅡ評分低于A組;C組患者CI、SVRI高于B組,EVLWI、APACHEⅡ評分低于B組(P0.05)。治療前3組患者Lac、PCT、CRP、BNP比較,差異無統(tǒng)計學(xué)意義(P0.05);治療后B、C組患者Lac、PCT、CRP、BNP低于A組,C組患者Lac、PCT、CRP、BNP低于B組(P0.05)。治療期間3組患者均無與藥物或血液灌流治療相關(guān)不良反應(yīng)發(fā)生。結(jié)論在膿毒性休克常規(guī)治療基礎(chǔ)上聯(lián)合應(yīng)用參麥注射液和血液灌流,能有效提高膿毒性休克患者心肌收縮能力、穩(wěn)定血流動力學(xué)、增加組織灌注、改善膿毒性休克患者病情。
[Abstract]:Objective to investigate the effect of Shenmai injection combined with hemoperfusion on hemodynamics and tissue perfusion in septic shock patients. Methods from January 2015 to August 2016, 60 patients with septic shock were selected from the Department of intensive Medicine of Shaoxing people's Hospital. 20 patients in group A were treated with conventional therapy for sepsis. The patients in group B were treated with Shenmai injection on the basis of group A and the patients in group C were treated with hemoperfusion on the basis of treatment in group B. The hemodynamic indexes (including cardiac index, peripheral vascular resistance index, extravascular pulmonary water index and EVLWI), acute physiological function and chronic health status scoring system 鈪，

本文編號：1858516