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腹腔鏡膽囊切除術(shù)治療急性結(jié)石性膽囊炎合并膽汁性腹膜炎的效果分析

發(fā)布時(shí)間:2018-05-05 11:19

  本文選題:腹腔鏡 + 急性結(jié)石性膽囊炎; 參考:《中華醫(yī)院感染學(xué)雜志》2017年24期


【摘要】:目的探討腹腔鏡膽囊切除術(shù)治療急性結(jié)石性膽囊炎合并膽汁性腹膜炎的術(shù)后感染效果。方法回顧性分析2015年1月-2017年1月于醫(yī)院行急性結(jié)石性膽囊炎合并膽汁性腹膜炎手術(shù)的63例患者的資料,按照患者的手術(shù)方法分組,利用開腹方法進(jìn)行手術(shù)的為對(duì)照組28例,利用腹腔鏡介導(dǎo)的方法進(jìn)行手術(shù)的為試驗(yàn)組35例,觀察分析兩組患者的治療效果。結(jié)果試驗(yàn)組的手術(shù)出血量與手術(shù)后3d的疼痛評(píng)分均低于對(duì)照組(P0.05);采用重復(fù)測量數(shù)據(jù)的方差分析顯示,對(duì)照組與試驗(yàn)組在手術(shù)前,手術(shù)后1、3、5、7d的體溫、白細(xì)胞計(jì)數(shù)(WBC)、C-反應(yīng)蛋白(CRP)、白細(xì)胞介素-6(IL-6),降鈣素(PCT)、腫瘤壞死因子-α(TNF-α)和紅細(xì)胞沉降率(ESR)比較,在不同時(shí)間點(diǎn)均差異有統(tǒng)計(jì)學(xué)意義,且試驗(yàn)組均低于對(duì)照組(P0.05);對(duì)照組與試驗(yàn)組的數(shù)據(jù)處理因素與時(shí)間之間均存在交互作用(P0.05)。結(jié)論利用腹腔鏡膽囊切除術(shù)治療急性結(jié)石性膽囊炎合并膽汁性腹膜炎的患者,可以降低患者手術(shù)后感染的風(fēng)險(xiǎn)。
[Abstract]:Objective to evaluate the effect of laparoscopic cholecystectomy (LC) on postoperative infection of acute calculous cholecystitis complicated with biliary peritonitis. Methods the data of 63 patients with acute calculous cholecystitis complicated with biliary peritonitis from January 2015 to January 2017 were analyzed retrospectively. The treatment effect of the two groups was observed and analyzed by laparoscopically mediated operation in 35 patients in the experimental group. Results the amount of operative bleeding and the pain score 3 days after operation in the trial group were lower than those in the control group (P 0.05), and the body temperature of the control group and the experimental group was 1: 3 and 5 days after operation before and after operation by means of variance analysis of repeated measurement data. The WBC count and erythrocyte sedimentation rate (ESRR) were significantly different from those of CRP, IL-6, PCT, TNF- 偽 and ESRs at different time points. The data processing factors and time of the control group and the control group were all lower than that of the control group, and the interaction between the data processing factors of the control group and the experimental group was P0.05. Conclusion Laparoscopic cholecystectomy can reduce the risk of postoperative infection in patients with acute calculous cholecystitis complicated with biliary peritonitis.
【作者單位】: 寧波市第二醫(yī)院肝膽胰外科;
【基金】:浙江省自然科學(xué)基金資助項(xiàng)目(Y2080096)
【分類號(hào)】:R657.4

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