本文選題：腦梗死 + 早期腸內營養(yǎng)　； 參考：《南昌大學》2013年碩士論文

【摘要】：目的：通過本課題的研究，，觀察早期腸內營養(yǎng)（24-48小時內）（EEF)或晚期腸內營養(yǎng)（DEF）（48小時-5天）對急性腦梗死患者的內分泌功能影響。以及內分泌功能是否會影響急性腦梗死患者的預后，進而闡明不同時期的腸內營養(yǎng)支持的激素水平對急性重癥腦梗死患者臨床轉歸的影響。 方法：①這是項非盲的隨機對照研究，完成急性重癥腦梗死患者的收集，根據(jù)排除標準確定入選患者。嚴重程度通過NIHSS預測，生存率通過急性生理學和慢性健康狀況評估。②34例患者給予早期營養(yǎng)組（24-48h內）和35例患者給予晚期營養(yǎng)組（48h-5天），并在入院時和入院后第6天、第12天監(jiān)測并記錄血漿TSH、FT3、FT4、皮質醇、睪酮水平。③完成不同營養(yǎng)組各激素水平的對比分析。④觀察各激素水平變化特點后，評價早期和晚期腸內營養(yǎng)在急性重癥腦梗死患者中對激素水平濃度變化的影響。 結果：TSH、FT3、FT4、睪酮（男性患者）濃度在早期營養(yǎng)組和晚期營養(yǎng)組的病人中都出現(xiàn)剛入院的第一天下降，但在晚期營養(yǎng)組中比早期營養(yǎng)組下降的更低(P0.05)，皮質醇濃度在晚期營養(yǎng)組明顯升高(P0.05)。在早期營養(yǎng)組中發(fā)現(xiàn)激素濃度的改變更小(P0.05)。 結論：早期腸內營養(yǎng)（EEF）對急性重癥腦梗死患者內分泌激素水平更有益處。減輕患者的炎癥代謝反應，有益于改善患者預后。
[Abstract]:Objective: to investigate the effects of early enteral nutrition (EPN) or late enteral nutrition (DEF) on the endocrine function of patients with acute cerebral infarction (ACI) within 24-48 hours (24-48 hours) or late enteral nutrition (DEF) for 48 hours-5 days. And whether endocrine function will affect the prognosis of patients with acute cerebral infarction, and then clarify the effect of enteral nutrition support hormone levels on the clinical outcome of patients with acute severe cerebral infarction. Methods: one was a non-blind randomized controlled study to collect patients with acute severe cerebral infarction and to determine the selected patients according to the exclusion criteria. Severity was predicted by NIHSS, survival rate was assessed by acute physiology and chronic health status. 234 patients were given early nutrition group for 24 to 48 hours) and 35 patients were given advanced nutrition group for 48 h-5 days and at admission and 6 days after admission. On the 12th day, the plasma levels of TSHT FT 3 FT 4, cortisol and testosterone were monitored and recorded. To evaluate the effect of early and late enteral nutrition on hormone levels in patients with acute severe cerebral infarction. Results: TSHFT3 FT4, testosterone (male patients) decreased on the first day of admission in both early and late nutrition groups. However, the concentration of cortisol in the late nutrition group was significantly higher than that in the early nutrition group, and the concentration of cortisol in the late nutrition group was significantly higher than that in the early nutrition group. In early nutrition group, the change of hormone concentration was smaller than that of P0.05. Conclusion: early enteral nutrition (EEF) is more beneficial to endocrine hormone level in patients with acute severe cerebral infarction. Reducing the inflammatory metabolic response is beneficial to improve the prognosis of patients.
【學位授予單位】：南昌大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R743.33

【引證文獻】

相關期刊論文 前1條

1 陸俊;王俊玫;李玉;;細致化護理對急診重癥腦梗死患者并發(fā)癥的影響分析[J];中國衛(wèi)生標準管理;2016年02期

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