經(jīng)抽吸導(dǎo)管冠脈閉塞段內(nèi)注入替羅非班治療急性心肌梗死
發(fā)布時(shí)間:2018-04-13 22:13
本文選題:急性心肌梗死 + 血栓抽吸導(dǎo)管 ; 參考:《實(shí)用醫(yī)學(xué)雜志》2016年18期
【摘要】:目的:研究經(jīng)抽吸導(dǎo)管在冠狀動脈閉塞段內(nèi)注入替羅非班對冠脈開通時(shí)間、開通后血流改善情況及患者近30 d不良事件發(fā)生率的影響。方法:我院近4年收住的97例經(jīng)冠脈造影證實(shí)罪犯血管為次全閉塞或完全閉塞的急性心肌梗死患者,隨機(jī)分為血栓抽吸組(A組)、閉塞段注入替羅非班+血栓抽吸組(B組)。比較兩組冠脈開通時(shí)間、開通后血流改善情況及患者近30 d不良事件發(fā)生率的影響。結(jié)果:A組冠脈開通時(shí)間較B組縮短(P0.05);B組血流達(dá)到TIMIⅢ級時(shí)間較A組縮短(P0.05);B組早期無復(fù)流發(fā)生率較A組低,早期血流達(dá)TIMIⅢ級比例較A組提高(P0.05);B組較A組30 d患者不良事件發(fā)生率下降,但差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:替羅非班在冠脈閉塞段直接注入可有效降低血管開通時(shí)間及早期無復(fù)流現(xiàn)象的發(fā)生率,改善冠脈灌注,不能降低30 d患者不良心血管事件發(fā)生率。
[Abstract]:Objective: to study the effects of injecting tirofiban into the occlusive segment of coronary artery via suction catheter on the duration of coronary artery opening, the improvement of blood flow and the incidence of adverse events in patients with coronary artery occlusion in the past 30 days.Methods: 97 patients with acute myocardial infarction (AMI) who were confirmed by coronary angiography to be subtotal occlusion or total occlusion were randomly divided into thrombotic aspiration group (group A) and tirofiban thrombotic aspiration group (group B).The time of coronary artery opening, the improvement of blood flow and the incidence of adverse events in 30 days were compared between the two groups.Results the duration of coronary artery opening in group A was shorter than that in group B (P 0.05). The time of blood flow to TIMI 鈪,
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