發(fā)布時(shí)間：2018-04-13 20:02

  本文選題：舒張壓 + 急性完全大腦中動(dòng)脈閉塞�。� 參考：《吉林大學(xué)》2013年碩士論文

【摘要】：目的：通過研究急性cMCAO患者的臨床轉(zhuǎn)歸與DBP以及其他危險(xiǎn)因素的相關(guān)性，從而為臨床上急性cMCAO的治療和預(yù)后判定提供新的證據(jù)和線索。 研究方法：本研究回顧性收集2011年1月~2012年11月在吉林大學(xué)第一臨床醫(yī)院神經(jīng)內(nèi)科收治的300例缺血性腦血管病住院患者，符合2010中國(guó)急性缺血性腦梗死診治診斷標(biāo)準(zhǔn)，使用Excel軟件收集資料。采用SPSS17.0統(tǒng)計(jì)學(xué)軟件，根據(jù)數(shù)據(jù)資料的不同分別采用t檢驗(yàn)、Wilcoxon秩和檢驗(yàn)、卡方檢驗(yàn)、Fisher精確概率檢驗(yàn)，p0.05為具有統(tǒng)計(jì)學(xué)意義。同時(shí)應(yīng)用二分類單因素和多因素Logistic回歸分析法和線性趨勢(shì)性檢驗(yàn)。 結(jié)果：300名患者平均年齡63.91±7.23歲，男性164名。急性cMCAO患者126名（42.0%），平均年齡67.72±6.91歲，男性58名。研究結(jié)果顯示：（1）年齡、性別、吸煙史、肥胖、心房纖顫和頸內(nèi)動(dòng)脈閉塞是急性cMCAO的相關(guān)危險(xiǎn)因素。（2）吸煙史、入院時(shí)DBP、入院時(shí)血糖和NIHSS評(píng)分是急性cMCAO死亡的相關(guān)危險(xiǎn)因素。（3）年齡、入院時(shí)DBP、入院時(shí)血糖及NIHSS評(píng)分是急性cMCAO住院患者死亡的主要相關(guān)危險(xiǎn)因素。（4）入院時(shí)DBP水平在100~109mmHg急性cMCAO死亡風(fēng)險(xiǎn)最低。線性趨勢(shì)性檢驗(yàn)結(jié)果顯示，，隨著入院時(shí)DBP水平的增加或者減少，死亡的危險(xiǎn)性也隨之增加（p=0.029，p0.05）。 結(jié)論：（1）急性cMCAO的主要相關(guān)危險(xiǎn)因素包括年齡、性別、吸煙史、肥胖、心房纖顫和頸內(nèi)動(dòng)脈閉塞等。（2）急性cMCAO不良預(yù)后的主要相關(guān)危險(xiǎn)因素包括年齡、入院時(shí)血糖水平、吸煙史、入院時(shí)DBP及NIHSS評(píng)分等。（3）入院時(shí)DBP水平低于100mmHg或者高于110mmHg時(shí)，急性cMCAO死亡危險(xiǎn)性明顯增高。隨著入院時(shí)DBP水平的增加或者減少，死亡的危險(xiǎn)性也隨之增加。
[Abstract]:Objective: to study the relationship between clinical outcome and DBP and other risk factors in patients with acute cMCAO, so as to provide new evidence and clues for clinical treatment and prognosis of acute cMCAO.Methods: from January 2011 to November 2012, 300 patients with ischemic cerebrovascular disease admitted in the Department of Neurology, the first Clinical Hospital of Jilin University, were collected retrospectively. The results were in accordance with the diagnostic criteria for acute ischemic cerebral infarction (ACI) in China in 2010 years.Collect data using Excel software.Using SPSS17.0 statistical software, t test and Wilcoxon rank sum test were used according to different data data, and Chi-square test showed that Fisher accurate probability test was statistically significant.At the same time, Logistic regression analysis and linear trend test were used.Results the average age of 300 patients was 63.91 鹵7.23 years old, 164 males.There were 126 patients with acute cMCAO (mean age 67.72 鹵6.91 years, male 58).The results showed that age, sex, smoking history, obesity, atrial fibrillation and internal carotid artery occlusion were the risk factors associated with acute cMCAO.DBP, blood glucose and NIHSS score were the main risk factors of death in patients with acute cMCAO on admission. (4) DBP level was the lowest in acute cMCAO at admission.The results of linear trend test showed that the risk of death increased with the increase or decrease of DBP level at admission.Conclusion the main risk factors associated with acute cMCAO include age, sex, smoking history, obesity, atrial fibrillation and internal carotid artery occlusion. The main risk factors for poor prognosis of acute cMCAO include age, blood glucose level at admission, smoking history.The risk of acute cMCAO death was significantly increased when the level of DBP was lower than 100mmHg or higher than that of 110mmHg at admission.As DBP levels increase or decrease at admission, the risk of death increases.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R743.3

【參考文獻(xiàn)】

相關(guān)期刊論文 前3條

1 孫蕓;徐愛華;莊嚴(yán);柳忠蘭;;香煙煙霧對(duì)大鼠腦血管細(xì)胞黏附分子1表達(dá)及腦梗死體積的影響[J];中國(guó)動(dòng)脈硬化雜志;2005年06期

2 李瑞華;劉磊;王澤穎;;缺血性腦卒中早期神經(jīng)功能惡化與血壓的關(guān)系[J];中華高血壓雜志;2011年05期

3 王擁軍;高血壓與腦卒中[J];中華心血管病雜志;2004年06期

本文編號(hào)：1745993