本文選題：膿毒癥 + 乳酸��； 參考：《中華醫(yī)院感染學(xué)雜志》2017年05期

【摘要】：目的觀察和分析乳酸和乳酸清除率在膿毒癥病情判斷、預(yù)后評(píng)估方面的效果,以期篩選出有價(jià)值的指標(biāo)協(xié)助臨床診療,降低病死率。方法選取2012年4月-2015年12月198例膿毒癥患者,根據(jù)入院后動(dòng)脈血乳酸水平,將納入的198例膿毒癥患者分為低乳酸組99例、中乳酸組65例和高乳酸組34例,參考預(yù)后分為生存組154例和死亡組44例,比較不同組別患者乳酸水平、乳酸清除率,血乳酸水平工作ROC曲線、影響預(yù)后因素的多元Logistic逐步回歸分析及乳酸、乳酸清除率與APACHEⅡ評(píng)分的相關(guān)性分析。結(jié)果低、中乳酸組生存率高于死亡率,差異有統(tǒng)計(jì)學(xué)意義(P0.05);低乳酸組生存率高于中、高乳酸組,死亡率低于中、高乳酸組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);6h、12h、24h、48h,生存組血乳酸水平低于入院時(shí),差異有統(tǒng)計(jì)學(xué)意義(P0.05),死亡組與入院時(shí)比較,差異無統(tǒng)計(jì)學(xué)意義,生存組血乳酸水平低于死亡組,乳酸清除率高于死亡組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);乳酸水平、乳酸清除率和APACHEⅡ評(píng)分是影響膿毒癥患者預(yù)后的獨(dú)立危險(xiǎn)因素,乳酸水平與APACHEⅡ評(píng)分呈正相關(guān)性(P0.05),乳酸清除率與APACHEⅡ評(píng)分呈負(fù)相關(guān)性(P0.05)。結(jié)論乳酸和乳酸清除率在膿毒癥病情判斷、預(yù)后評(píng)估方面意義重大,能有效反映病情程度、指導(dǎo)臨床治療、預(yù)測結(jié)局,且檢測方便、簡捷、經(jīng)濟(jì),值得臨床推廣。
[Abstract]:Objective to observe and analyze the efficacy of lactic acid and lactate clearance rate in evaluating the condition and prognosis of sepsis in order to select valuable indexes to help clinical diagnosis and treatment and reduce mortality.Methods 198 patients with sepsis from April 2012 to December 2015 were randomly divided into low lactic acid group (n = 99), moderate lactic acid group (n = 65) and high lactic acid group (n = 34).The prognosis was divided into survival group (n = 154) and death group (n = 44). The ROC curves of lactate level, lactate clearance rate, blood lactate level, multiple Logistic stepwise regression analysis and lactic acid were compared.Correlation analysis between lactate clearance rate and APACHE 鈪，

本文編號(hào)：1744814