本文選題：吸煙 + 顱腦損傷��； 參考：《寧夏醫(yī)科大學(xué)》2013年碩士論文

【摘要】：目的：了解吸煙對(duì)重型顱腦損傷患者肺部感染及預(yù)后的影響，，為重型顱腦損傷患者的臨床救治提供指導(dǎo)。 方法：選擇2006.1-2012.6入住寧夏醫(yī)科大學(xué)總醫(yī)院神經(jīng)外科的早期腦疝患者236例，其中51例并發(fā)肺部感染，根據(jù)是否并發(fā)肺部感染將患者分為感染組和對(duì)照組，其中感染組共51例，對(duì)照組181例。兩組病例之間在GCS評(píng)分與意識(shí)障礙的嚴(yán)重程度兩方面采用方差分析沒(méi)有統(tǒng)計(jì)學(xué)差異。兩組病例之間氣管切開(kāi)方面采用卡方檢驗(yàn)沒(méi)有統(tǒng)計(jì)學(xué)差異。兩組間性別運(yùn)用卡方檢驗(yàn)和年齡運(yùn)用t檢驗(yàn)均無(wú)統(tǒng)計(jì)學(xué)差異（P均＞0.05），具有可比性，兩組患者病情嚴(yán)重程度，以及治療方案上相對(duì)一致。將兩組患者是否吸煙、吸煙時(shí)間以及吸煙量的情況進(jìn)行統(tǒng)計(jì)。 結(jié)果：感染組吸煙率為60.8%，對(duì)照組吸煙率為35.7%，兩組間差異有統(tǒng)計(jì)學(xué)意義，P=0.001。單因素回歸分析表明：吸煙者患病風(fēng)險(xiǎn)是不吸煙者的2.794倍。以小于等于5年、大于5年小于等于10年、大于10小于等于15年、大于15年將患者分為四組，兩組間比較均存在統(tǒng)計(jì)學(xué)差異，P=0.001。單因素回歸分析表明：吸煙年限提高五年患病風(fēng)險(xiǎn)是不吸煙者的1.39倍。吸煙量未見(jiàn)統(tǒng)計(jì)學(xué)差異。 結(jié)論：吸煙是重型顱腦損傷患者肺部感染的危險(xiǎn)因素，患者吸煙后顱腦損傷肺部感染風(fēng)險(xiǎn)比不吸煙患者提高。吸煙時(shí)間是重型顱腦損傷患者肺部感染的危險(xiǎn)因素，隨著吸煙時(shí)間增加，患者顱腦損傷后肺部感染風(fēng)險(xiǎn)提高。
[Abstract]:Objective: to investigate the effect of smoking on pulmonary infection and prognosis in patients with severe craniocerebral injury.Methods: 236 patients with early brain hernia admitted to the Neurosurgery Department of Ningxia Medical University General Hospital from June 2001 to June 2012.6 were selected. Among them, 51 cases were complicated with pulmonary infection. The patients were divided into infection group and control group according to whether they were complicated with pulmonary infection, among which 51 cases were infected group.Control group 181 cases.There was no statistical difference in GCS score and severity of consciousness disorder between the two groups.There was no statistical difference between the two groups in tracheotomy by chi-square test.There was no statistical difference between the two groups in sex use chi-square test and age use t test (P > 0.05), which was comparable. The severity of the disease and the treatment plan of the two groups were relatively consistent.The two groups of patients with smoking, smoking time and smoking volume were counted.Results: the smoking rate of the infected group was 60.8 and that of the control group was 35.7.The difference between the two groups was statistically significant.Univariate regression analysis showed that smokers were 2.794 times more at risk than non-smokers.The patients were divided into four groups: less than 5 years, more than 5 years less than 10 years, more than 10 less than 15 years, and more than 15 years. There was statistical difference between the two groups.Univariate regression analysis showed that smoking years increased the risk of disease by 1.39 times than that of non-smokers.There was no statistical difference in smoking.Conclusion: smoking is a risk factor for lung infection in patients with severe craniocerebral injury.Smoking time was a risk factor for lung infection in patients with severe craniocerebral injury. With the increase of smoking time, the risk of pulmonary infection increased after craniocerebral injury.
【學(xué)位授予單位】：寧夏醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R651.15

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