One important and growing direction in modern medicine is the diagnosis of diseases on their early stage.On time recognition of body disorders can prevent fast worsen of illnesses,help to cure them successfully.However,at the same time,early-stage diagnosis is a very difficult task because,at this stage,diseases pretty often do not display any symptoms.This is a reason why nowadays medicine seeks for new ways of illness recognition and modern science is developing directions to help to solve suc... 

【文章來源】：上海交通大學上海市 211工程院校 985工程院校 教育部直屬院校

【文章頁數(shù)】：48 頁

【學位級別】：碩士

【文章目錄】：
abstract
1 Introduction
2 Background
    2.1 PAFC in vivo detection of circulating cells
        2.1.1 History of the method development
        2.1.2 Concept of photoacoustic flow cytometry
    2.2 Basic concepts of white blood cells
    2.3 Basic concepts of red blood cells
    2.4 Malignant tumor:Melanoma cells
3 Materials and method
    3.1 Experimental setup
    3.2 Cells cultures and animal model
        3.2.1 The Melanoma cells sample preparation
        3.2.2 The red blood cells and white blood cells sample preparation
        3.2.3 Animal model preparation
        3.2.4 Method and its feasibility
4 Experimental protocol
    4.1 Pre-experimental stage
    4.2 Melanoma cells detection stage
        4.2.1 Melanoma cells detection stage in vitro part
        4.2.2 Melanoma cells detection stage in vivo part
    4.3 RBCs and WBCs detection stage
        4.3.1 RBCs and WBCs detection stage in vitro part
        4.3.2 RBCs and WBCs detection stage in vivo part
5 Signal processing
    5.1 Wavelet transformation
    5.2 Procedure of signal averaging
    5.3 Reducing the laser operation noise
    5.4 Peak to peak approach
6 Results
    6.1 Results of melanoma cells detection
    6.2 Results of RBCs and WBCs detection
Conclusion
Discussion
References



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